| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 2,4-dimethoxyaniline.hcl 40.4 um perturbation at 3 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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72 genes differentially expressed following the CRCGN014_HEPG2_3H:A15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 6.04868 |
| ADRB2 | adrenoceptor beta 2, surface | 4.93625 |
| MAMLD1 | mastermind-like domain containing 1 | 4.75859 |
| STK10 | serine/threonine kinase 10 | 4.72164 |
| SFTPB | surfactant protein B | 4.51794 |
| MAP7 | microtubule-associated protein 7 | 4.23018 |
| PLSCR1 | phospholipid scramblase 1 | 4.07129 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.06695 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 3.86683 |
| CYCS | cytochrome c, somatic | 3.73049 |
| MYLK | myosin light chain kinase | 3.65964 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.46567 |
| PTK2 | protein tyrosine kinase 2 | 3.19181 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 2.96451 |
| E2F2 | E2F transcription factor 2 | 2.90335 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 2.70789 |
| EGF | epidermal growth factor | 2.57884 |
| CLOCK | clock circadian regulator | 2.42837 |
| MYOM1 | myomesin 1 | 2.34413 |
| CA10 | carbonic anhydrase X | 2.32244 |
| MAGEB2 | melanoma antigen family B2 | 2.30484 |
| PLA2G12A | phospholipase A2, group XIIA | 2.23255 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 2.19005 |
| CD63 | CD63 molecule | 2.1628 |
| ONECUT1 | one cut homeobox 1 | 2.15327 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 2.14894 |
| SMUG1 | single-strand-selective monofunctional uracil-DNA glycosylase 1 | 2.14201 |
| NCOA4 | nuclear receptor coactivator 4 | 2.12142 |
| LOC122526780 | uncharacterized LOC122526780 | 2.11892 |
| RTN2 | reticulon 2 | 2.10565 |
| RRAGA | Ras-related GTP binding A | 2.09765 |
| ATG7 | autophagy related 7 | 2.08613 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 2.08558 |
| GABRA6 | gamma-aminobutyric acid (GABA) A receptor, alpha 6 | 2.06928 |
| TSPAN5 | tetraspanin 5 | 2.06527 |
| SLC25A46 | solute carrier family 25, member 46 | 2.06353 |
| COPZ1 | coatomer protein complex, subunit zeta 1 | 2.01549 |
| USP13 | ubiquitin specific peptidase 13 (isopeptidase T-3) | 2.00523 |
| GOLM1 | golgi membrane protein 1 | 2.00356 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -10.0 |
| LDHD | lactate dehydrogenase D | -8.40417 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -7.35899 |
| KDM3A | lysine (K)-specific demethylase 3A | -6.35362 |
| DNM1L | dynamin 1-like | -5.15562 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -5.12996 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -4.92081 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -4.42894 |
| ALAS1 | 5'-aminolevulinate synthase 1 | -3.68639 |
| MACF1 | microtubule-actin crosslinking factor 1 | -3.28148 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -3.23654 |
| TXNDC9 | thioredoxin domain containing 9 | -3.19535 |
| RHEB | Ras homolog enriched in brain | -3.18278 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -3.02023 |
| TRIB3 | tribbles pseudokinase 3 | -2.8828 |
| CSK | c-src tyrosine kinase | -2.70344 |
| NVL | nuclear VCP-like | -2.68538 |
| GPBP1L1 | GC-rich promoter binding protein 1-like 1 | -2.44458 |
| ENO2 | enolase 2 (gamma, neuronal) | -2.42566 |
| GLOD4 | glyoxalase domain containing 4 | -2.37088 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -2.35129 |
| PTCD3 | pentatricopeptide repeat domain 3 | -2.20301 |
| PPCS | phosphopantothenoylcysteine synthetase | -2.1771 |
| ATP6V0E2 | ATPase, H+ transporting V0 subunit e2 | -2.15748 |
| TOMM70 | translocase of outer mitochondrial membrane 70 | -2.1281 |
| ESYT1 | extended synaptotagmin-like protein 1 | -2.08256 |
| SERGEF | secretion regulating guanine nucleotide exchange factor | -2.07037 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | -2.06892 |
| LAMTOR2 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 | -2.05081 |
| SNRPE | small nuclear ribonucleoprotein polypeptide E | -2.02528 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.01417 |
| AMN | amnion associated transmembrane protein | -2.01409 |
| NUP107 | nucleoporin 107kDa | -2.00643 |
