| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | oxyquinoline 40.2 um perturbation at 3 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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73 genes differentially expressed following the CRCGN014_HEPG2_3H:A17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 7.22298 |
| DDIT4 | DNA-damage-inducible transcript 4 | 5.88978 |
| KDM3A | lysine (K)-specific demethylase 3A | 4.96564 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 3.88821 |
| SFTPB | surfactant protein B | 3.87488 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.63781 |
| UBQLN2 | ubiquilin 2 | 3.60606 |
| HMOX1 | heme oxygenase 1 | 3.52686 |
| PRR15L | proline rich 15-like | 3.5052 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.40728 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 3.40215 |
| CNPY3 | canopy FGF signaling regulator 3 | 3.36307 |
| TXNRD1 | thioredoxin reductase 1 | 3.15347 |
| HYOU1 | hypoxia up-regulated 1 | 3.116 |
| STIMATE | STIM activating enhancer | 3.03767 |
| TXNL4B | thioredoxin-like 4B | 2.99315 |
| LAP3 | leucine aminopeptidase 3 | 2.96917 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 2.89259 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta | 2.80929 |
| KIFBP | kinesin family binding protein | 2.74033 |
| EVL | Enah/Vasp-like | 2.7148 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 2.64173 |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like | 2.63394 |
| MAP7 | microtubule-associated protein 7 | 2.6321 |
| ZBTB18 | zinc finger and BTB domain containing 18 | 2.558 |
| HSPA1A | heat shock 70kDa protein 1A | 2.52372 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 2.41551 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 2.40339 |
| ZNF589 | zinc finger protein 589 | 2.36933 |
| CDK6 | cyclin-dependent kinase 6 | 2.35203 |
| ZFP36 | ZFP36 ring finger protein | 2.2945 |
| TCTA | T-cell leukemia translocation altered | 2.22313 |
| ABHD6 | abhydrolase domain containing 6 | 2.19928 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 2.15993 |
| ABHD4 | abhydrolase domain containing 4 | 2.15514 |
| FHL2 | four and a half LIM domains 2 | 2.13502 |
| MMP2 | matrix metallopeptidase 2 | 2.03937 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -6.58564 |
| ZNF586 | zinc finger protein 586 | -5.98687 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -3.96082 |
| GRWD1 | glutamate-rich WD repeat containing 1 | -3.62345 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -3.59668 |
| NGRN | neugrin, neurite outgrowth associated | -3.56216 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.48826 |
| PCNA | proliferating cell nuclear antigen | -3.27686 |
| CCNB1 | cyclin B1 | -3.23794 |
| CCNH | cyclin H | -3.16819 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -3.15236 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.91607 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -2.86332 |
| FBXO7 | F-box protein 7 | -2.78523 |
| GNAS | GNAS complex locus | -2.69661 |
| TCEAL4 | transcription elongation factor A (SII)-like 4 | -2.66741 |
| PRPF4 | pre-mRNA processing factor 4 | -2.61729 |
| CCDC86 | coiled-coil domain containing 86 | -2.56257 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -2.52974 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.48691 |
| CSK | c-src tyrosine kinase | -2.46504 |
| UGDH | UDP-glucose 6-dehydrogenase | -2.43892 |
| CDC20 | cell division cycle 20 | -2.43513 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -2.42539 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.3691 |
| RPS6KB2 | ribosomal protein S6 kinase, 70kDa, polypeptide 2 | -2.3523 |
| MPC2 | mitochondrial pyruvate carrier 2 | -2.35188 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -2.34592 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -2.22199 |
| COG7 | component of oligomeric golgi complex 7 | -2.19892 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -2.18083 |
| COPS4 | COP9 signalosome subunit 4 | -2.17847 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -2.10324 |
| LBHD1 | LBH domain containing 1 | -2.05501 |
| DSN1 | DSN1, MIS12 kinetochore complex component | -2.05312 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.02849 |
