| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | ciprofibrate 21.38 um perturbation at 3 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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69 genes differentially expressed following the CRCGN014_HEPG2_3H:A18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PMM2 | phosphomannomutase 2 | 5.25011 |
| MEST | mesoderm specific transcript | 4.613 |
| MAP7 | microtubule-associated protein 7 | 4.52986 |
| SHB | Src homology 2 domain containing adaptor protein B | 4.11199 |
| NOTCH1 | notch 1 | 3.72833 |
| UBQLN2 | ubiquilin 2 | 3.46158 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 3.4253 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 3.37845 |
| MSRA | methionine sulfoxide reductase A | 3.30339 |
| BZW2 | basic leucine zipper and W2 domains 2 | 3.23411 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.23042 |
| SOCS2 | suppressor of cytokine signaling 2 | 3.20992 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 3.03828 |
| CYCS | cytochrome c, somatic | 2.98282 |
| NOSIP | nitric oxide synthase interacting protein | 2.97232 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 2.91153 |
| CBR3 | carbonyl reductase 3 | 2.74043 |
| MMP2 | matrix metallopeptidase 2 | 2.58868 |
| CREG1 | cellular repressor of E1A-stimulated genes 1 | 2.49497 |
| GPATCH8 | G patch domain containing 8 | 2.41092 |
| TOR1B | torsin family 1, member B (torsin B) | 2.38363 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | 2.3554 |
| KLHDC2 | kelch domain containing 2 | 2.33386 |
| MAMLD1 | mastermind-like domain containing 1 | 2.32018 |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B | 2.28602 |
| CPSF4 | cleavage and polyadenylation specific factor 4, 30kDa | 2.2674 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.20293 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | 2.20055 |
| SEC24C | SEC24 family member C | 2.19635 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 2.18269 |
| STIMATE | STIM activating enhancer | 2.17492 |
| EPN2 | epsin 2 | 2.15105 |
| TCTA | T-cell leukemia translocation altered | 2.08706 |
| ZNF768 | zinc finger protein 768 | 2.0317 |
| RXYLT1 | ribitol xylosyltransferase 1 | 2.01286 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -8.4975 |
| ZNF586 | zinc finger protein 586 | -5.26667 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.87733 |
| SLC35F2 | solute carrier family 35, member F2 | -4.65461 |
| CDC20 | cell division cycle 20 | -4.23983 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -4.22935 |
| SCAND1 | SCAN domain containing 1 | -4.16059 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.98023 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -3.91973 |
| LYPLA1 | lysophospholipase I | -3.7834 |
| ADI1 | acireductone dioxygenase 1 | -3.77065 |
| CD320 | CD320 molecule | -3.42581 |
| DNM1L | dynamin 1-like | -3.28373 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | -2.99118 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -2.94759 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.92851 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | -2.80891 |
| LDHD | lactate dehydrogenase D | -2.53816 |
| CAB39 | calcium binding protein 39 | -2.33324 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | -2.30874 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -2.28974 |
| ATP6V1H | ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H | -2.28286 |
| EBNA1BP2 | EBNA1 binding protein 2 | -2.26913 |
| EAPP | E2F-associated phosphoprotein | -2.21602 |
| CCNB1 | cyclin B1 | -2.17452 |
| TLR4 | toll-like receptor 4 | -2.10769 |
| APOE | apolipoprotein E | -2.08487 |
| ECM2 | extracellular matrix protein 2, female organ and adipocyte specific | -2.07193 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -2.07068 |
| CETN3 | centrin, EF-hand protein, 3 | -2.03016 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -2.02762 |
| PDGFRL | platelet-derived growth factor receptor-like | -2.01356 |
| CRYZ | crystallin, zeta (quinone reductase) | -2.01322 |
| NDUFA7 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa | -2.00325 |
