CRCGN014_HEPG2_3H:A21 Gene Set
Genes
48 genes differentially expressed following the CRCGN014_HEPG2_3H:A21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CHMP6
|
charged multivesicular body protein 6
|
6.16485
|
|
MSRA
|
methionine sulfoxide reductase A
|
5.99486
|
|
STK10
|
serine/threonine kinase 10
|
5.67444
|
|
NOTCH1
|
notch 1
|
5.40547
|
|
MAP7
|
microtubule-associated protein 7
|
4.27881
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
4.17638
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.79848
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.64207
|
|
SLC75A1
|
solute carrier family 75 member 1
|
3.38729
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.28371
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.14411
|
|
PLSCR3
|
phospholipid scramblase 3
|
3.09688
|
|
SFTPB
|
surfactant protein B
|
2.79742
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.77814
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
2.75104
|
|
CHN1
|
chimerin 1
|
2.63636
|
|
CSK
|
c-src tyrosine kinase
|
2.61246
|
|
CCNA1
|
cyclin A1
|
2.54944
|
|
RPS6KA1
|
ribosomal protein S6 kinase, 90kDa, polypeptide 1
|
2.33188
|
|
PRKCH
|
protein kinase C, eta
|
2.32195
|
|
KIF20A
|
kinesin family member 20A
|
2.27024
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.2312
|
|
WDTC1
|
WD and tetratricopeptide repeats 1
|
2.18213
|
|
POLG2
|
polymerase (DNA directed), gamma 2, accessory subunit
|
2.18103
|
|
CCDC85B
|
coiled-coil domain containing 85B
|
2.06207
|
|
EVL
|
Enah/Vasp-like
|
2.00633
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-6.09427
|
|
ZNF586
|
zinc finger protein 586
|
-6.0301
|
|
CD320
|
CD320 molecule
|
-5.26514
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-3.71449
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.71324
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-3.64716
|
|
LDHD
|
lactate dehydrogenase D
|
-3.63905
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.30231
|
|
NFKBIA
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
|
-3.22078
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.21052
|
|
STAMBP
|
STAM binding protein
|
-3.16285
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-3.10696
|
|
TCEAL4
|
transcription elongation factor A (SII)-like 4
|
-2.99115
|
|
MTA1
|
metastasis associated 1
|
-2.98604
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-2.91111
|
|
COG7
|
component of oligomeric golgi complex 7
|
-2.85402
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
-2.46635
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.36755
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.31999
|
|
TWF2
|
twinfilin actin binding protein 2
|
-2.16703
|
|
TSKU
|
tsukushi, small leucine rich proteoglycan
|
-2.06956
|
|
SNED1
|
sushi, nidogen and EGF-like domains 1
|
-2.03164
|
