CRCGN014_HEPG2_3H:A23 Gene Set
Genes
42 genes differentially expressed following the CRCGN014_HEPG2_3H:A23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
7.19371
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
6.9896
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
6.07918
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
3.63444
|
|
E2F2
|
E2F transcription factor 2
|
3.59607
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.51349
|
|
ZNF589
|
zinc finger protein 589
|
3.49676
|
|
CBR3
|
carbonyl reductase 3
|
3.44045
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
3.22562
|
|
LCN2
|
lipocalin 2
|
3.00393
|
|
COG4
|
component of oligomeric golgi complex 4
|
2.99129
|
|
USP6NL
|
USP6 N-terminal like
|
2.8139
|
|
PLSCR1
|
phospholipid scramblase 1
|
2.75904
|
|
GPATCH8
|
G patch domain containing 8
|
2.7077
|
|
CYCS
|
cytochrome c, somatic
|
2.67209
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.59499
|
|
CSK
|
c-src tyrosine kinase
|
2.48419
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.35899
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
2.32456
|
|
SORBS3
|
sorbin and SH3 domain containing 3
|
2.32308
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.31425
|
|
SFTPB
|
surfactant protein B
|
2.28184
|
|
MAP7
|
microtubule-associated protein 7
|
2.10236
|
|
PTK2
|
protein tyrosine kinase 2
|
2.07538
|
|
GALT
|
galactose-1-phosphate uridylyltransferase
|
2.05038
|
|
WDTC1
|
WD and tetratricopeptide repeats 1
|
2.01718
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-7.02664
|
|
CCNB1
|
cyclin B1
|
-5.53798
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.13886
|
|
LDHD
|
lactate dehydrogenase D
|
-3.66368
|
|
CCNH
|
cyclin H
|
-3.41157
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-3.38484
|
|
ZNF586
|
zinc finger protein 586
|
-3.04117
|
|
GNAS
|
GNAS complex locus
|
-2.76094
|
|
FAT1
|
FAT atypical cadherin 1
|
-2.6287
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-2.60436
|
|
CDC20
|
cell division cycle 20
|
-2.53325
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.36363
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.14816
|
|
MTA1
|
metastasis associated 1
|
-2.14192
|
|
CCNB2
|
cyclin B2
|
-2.06101
|
|
HSPA8
|
heat shock 70kDa protein 8
|
-2.04653
|
