| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | UnTrt perturbation at 3 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
58 genes differentially expressed following the CRCGN014_HEPG2_3H:B03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CYCS | cytochrome c, somatic | 6.3541 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 5.17338 |
| CBR3 | carbonyl reductase 3 | 4.7654 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 4.61361 |
| GPATCH8 | G patch domain containing 8 | 4.2576 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.82687 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 3.81429 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 3.10894 |
| NOSIP | nitric oxide synthase interacting protein | 2.95045 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.91435 |
| CHN1 | chimerin 1 | 2.90584 |
| MEST | mesoderm specific transcript | 2.90185 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | 2.79544 |
| KIF20A | kinesin family member 20A | 2.61896 |
| MAMLD1 | mastermind-like domain containing 1 | 2.58462 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 2.44606 |
| DHDDS | dehydrodolichyl diphosphate synthase | 2.43895 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.36087 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 2.25387 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 | 2.24495 |
| RBKS | ribokinase | 2.22393 |
| ATP11B | ATPase, class VI, type 11B | 2.18571 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 2.12501 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 2.11172 |
| KIF14 | kinesin family member 14 | 2.11167 |
| PCDHB11 | protocadherin beta 11 | 2.0955 |
| FMOD | fibromodulin | 2.09501 |
| AP5M1 | adaptor-related protein complex 5, mu 1 subunit | 2.0891 |
| KIF1B | kinesin family member 1B | 2.07756 |
| SMU1 | smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) | 2.07613 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -10.0 |
| ZNF586 | zinc finger protein 586 | -6.28235 |
| CCDC86 | coiled-coil domain containing 86 | -5.03592 |
| DERA | deoxyribose-phosphate aldolase (putative) | -4.84896 |
| GOLT1B | golgi transport 1B | -4.51077 |
| SLC35F2 | solute carrier family 35, member F2 | -3.86766 |
| GNAS | GNAS complex locus | -3.72607 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.69324 |
| TUBB6 | tubulin, beta 6 class V | -3.51247 |
| CCNB2 | cyclin B2 | -3.18248 |
| SNX11 | sorting nexin 11 | -3.11703 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -3.09282 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.84186 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -2.77632 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -2.71216 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.69154 |
| CMAS | cytidine monophosphate N-acetylneuraminic acid synthetase | -2.59251 |
| CTSD | cathepsin D | -2.56924 |
| FGFR4 | fibroblast growth factor receptor 4 | -2.53446 |
| RECQL | RecQ helicase-like | -2.33438 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | -2.28057 |
| IL23A | interleukin 23, alpha subunit p19 | -2.17377 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.11092 |
| CD320 | CD320 molecule | -2.10547 |
| SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain | -2.06316 |
| PFN1 | profilin 1 | -2.04373 |
| ZNF354A | zinc finger protein 354A | -2.04098 |
| GPSM3 | G-protein signaling modulator 3 | -2.04003 |
