CRCGN014_HEPG2_3H:B04 Gene Set
Genes
50 genes differentially expressed following the CRCGN014_HEPG2_3H:B04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CHMP6
|
charged multivesicular body protein 6
|
8.27817
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
6.45511
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
5.20601
|
|
MAP7
|
microtubule-associated protein 7
|
4.48939
|
|
MYLK
|
myosin light chain kinase
|
3.9514
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
3.2196
|
|
STIMATE
|
STIM activating enhancer
|
3.16566
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
3.13635
|
|
XPNPEP1
|
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
|
3.12653
|
|
UBQLN2
|
ubiquilin 2
|
3.1188
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
3.08636
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
3.06939
|
|
PLSCR3
|
phospholipid scramblase 3
|
3.02705
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.86833
|
|
DRAP1
|
DR1-associated protein 1 (negative cofactor 2 alpha)
|
2.73912
|
|
STXBP2
|
syntaxin binding protein 2
|
2.51429
|
|
NUP133
|
nucleoporin 133kDa
|
2.50099
|
|
HOXA10
|
homeobox A10
|
2.48309
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
2.46384
|
|
CBR3
|
carbonyl reductase 3
|
2.36474
|
|
STK10
|
serine/threonine kinase 10
|
2.31862
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.29331
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
2.24453
|
|
RXYLT1
|
ribitol xylosyltransferase 1
|
2.23637
|
|
CEP57
|
centrosomal protein 57kDa
|
2.15117
|
|
PSMB8
|
proteasome (prosome, macropain) subunit, beta type, 8
|
2.05332
|
|
SAA2
|
serum amyloid A2
|
2.03124
|
|
EXOSC4
|
exosome component 4
|
2.01017
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-10.0
|
|
CCNB2
|
cyclin B2
|
-6.12192
|
|
WDR7
|
WD repeat domain 7
|
-4.89114
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-3.73305
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-3.60652
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-3.32384
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-3.24789
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-3.10806
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-3.05972
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-3.0401
|
|
CDC25B
|
cell division cycle 25B
|
-3.03464
|
|
ISOC1
|
isochorismatase domain containing 1
|
-2.96538
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.91819
|
|
CDC20
|
cell division cycle 20
|
-2.77767
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.73615
|
|
TLR4
|
toll-like receptor 4
|
-2.32501
|
|
GNAS
|
GNAS complex locus
|
-2.28826
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.19416
|
|
CCNB1
|
cyclin B1
|
-2.12277
|
|
ZNF34
|
zinc finger protein 34
|
-2.04304
|
|
NEO1
|
neogenin 1
|
-2.02603
|
|
ZNF586
|
zinc finger protein 586
|
-2.01351
|
