| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | dl-menthol 41.0 um perturbation at 3 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
124 genes differentially expressed following the CRCGN014_HEPG2_3H:B05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 7.25822 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 5.01076 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.66425 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.63455 |
| SQOR | sulfide quinone oxidoreductase | 4.4715 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 3.66696 |
| CEP57 | centrosomal protein 57kDa | 3.61785 |
| SHB | Src homology 2 domain containing adaptor protein B | 3.43608 |
| CYCS | cytochrome c, somatic | 3.17655 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 3.05499 |
| SNX7 | sorting nexin 7 | 3.01236 |
| EDN1 | endothelin 1 | 2.96894 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.92778 |
| FZD1 | frizzled class receptor 1 | 2.79318 |
| TCTA | T-cell leukemia translocation altered | 2.73515 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 2.61478 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 2.6023 |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 | 2.60139 |
| LIN37 | lin-37 DREAM MuvB core complex component | 2.59062 |
| ZNF589 | zinc finger protein 589 | 2.58947 |
| SMIM40 | small integral membrane protein 40 | 2.53279 |
| ZNF112 | zinc finger protein 112 | 2.52224 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.49322 |
| TRIP10 | thyroid hormone receptor interactor 10 | 2.48225 |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) | 2.47962 |
| RRAGA | Ras-related GTP binding A | 2.47007 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.42791 |
| TBXA2R | thromboxane A2 receptor | 2.4085 |
| NUCB2 | nucleobindin 2 | 2.40842 |
| SCYL3 | SCY1-like 3 (S. cerevisiae) | 2.34207 |
| FILIP1L | filamin A interacting protein 1-like | 2.33766 |
| STX6 | syntaxin 6 | 2.32794 |
| DCTN3 | dynactin 3 (p22) | 2.29046 |
| SNAP29 | synaptosomal-associated protein, 29kDa | 2.28691 |
| ZNF512B | zinc finger protein 512B | 2.28164 |
| CRIP2 | cysteine-rich protein 2 | 2.27047 |
| ARHGAP29 | Rho GTPase activating protein 29 | 2.2686 |
| NIT1 | nitrilase 1 | 2.24926 |
| HDAC9 | histone deacetylase 9 | 2.24195 |
| MMP2 | matrix metallopeptidase 2 | 2.24126 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.23987 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 2.20632 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | 2.20266 |
| SLAMF8 | SLAM family member 8 | 2.1649 |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B | 2.16046 |
| CCNF | cyclin F | 2.15897 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 2.13364 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.13032 |
| ZFYVE21 | zinc finger, FYVE domain containing 21 | 2.10935 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 2.10805 |
| UEVLD | UEV and lactate/malate dehyrogenase domains | 2.10791 |
| RNF115 | ring finger protein 115 | 2.10493 |
| LAP3 | leucine aminopeptidase 3 | 2.10099 |
| ZBED2 | zinc finger, BED-type containing 2 | 2.08352 |
| ZNF148 | zinc finger protein 148 | 2.0742 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 2.06545 |
| FAM50B | family with sequence similarity 50, member B | 2.05441 |
| OCRL | oculocerebrorenal syndrome of Lowe | 2.03956 |
| CACNB3 | calcium channel, voltage-dependent, beta 3 subunit | 2.03373 |
| SMTN | smoothelin | 2.01237 |
| PTMS | parathymosin | 2.00908 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 | 2.00214 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -10.0 |
| VDAC1 | voltage-dependent anion channel 1 | -5.82377 |
| KDM3A | lysine (K)-specific demethylase 3A | -5.65315 |
| SLC35F2 | solute carrier family 35, member F2 | -5.38692 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -5.02509 |
| ENOPH1 | enolase-phosphatase 1 | -5.00668 |
| CDC20 | cell division cycle 20 | -4.91525 |
| LDHD | lactate dehydrogenase D | -4.83866 |
| ZNF586 | zinc finger protein 586 | -4.69221 |
| HAT1 | histone acetyltransferase 1 | -4.39267 |
| CD320 | CD320 molecule | -4.33838 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -4.31551 |
| GNAS | GNAS complex locus | -3.69407 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.63842 |
| CSK | c-src tyrosine kinase | -3.60487 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -3.36987 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -3.34542 |
| TRIB3 | tribbles pseudokinase 3 | -3.30167 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -3.22145 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -3.14599 |
| HNRNPH2 | heterogeneous nuclear ribonucleoprotein H2 (H') | -3.09563 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | -2.98099 |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 | -2.97849 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.94884 |
| FBXO7 | F-box protein 7 | -2.90504 |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D | -2.80419 |
| PRPF4 | pre-mRNA processing factor 4 | -2.7558 |
| OLA1 | Obg-like ATPase 1 | -2.66216 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa | -2.55732 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -2.49688 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | -2.45781 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | -2.40914 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.36334 |
| FTL | ferritin, light polypeptide | -2.34527 |
| FAM171A1 | family with sequence similarity 171, member A1 | -2.34515 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.32524 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -2.3124 |
| MRPL23 | mitochondrial ribosomal protein L23 | -2.30101 |
| GLOD4 | glyoxalase domain containing 4 | -2.28189 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -2.27175 |
| JMJD1C | jumonji domain containing 1C | -2.26051 |
| PPY | pancreatic polypeptide | -2.22842 |
| PGAP2 | post-GPI attachment to proteins 2 | -2.21318 |
| NLRP1 | NLR family, pyrin domain containing 1 | -2.18296 |
| LOC124900388 | uncharacterized LOC124900388 | -2.1671 |
| BLM | Bloom syndrome, RecQ helicase-like | -2.15973 |
| NUTF2 | nuclear transport factor 2 | -2.13437 |
| ARID4A | AT rich interactive domain 4A (RBP1-like) | -2.10358 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 | -2.09957 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | -2.09731 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -2.09012 |
| RNASE7 | ribonuclease, RNase A family, 7 | -2.06832 |
| METTL9 | methyltransferase like 9 | -2.05901 |
| PLP1 | proteolipid protein 1 | -2.04619 |
| FKBP3 | FK506 binding protein 3, 25kDa | -2.04474 |
| EML3 | echinoderm microtubule associated protein like 3 | -2.04336 |
| TFF1 | trefoil factor 1 | -2.04168 |
| ARF5 | ADP-ribosylation factor 5 | -2.03299 |
| HSPBP1 | HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 | -2.03023 |
| MED28 | mediator complex subunit 28 | -2.02681 |
| SLIRP | SRA stem-loop interacting RNA binding protein | -2.0241 |
| BIN3 | bridging integrator 3 | -2.01746 |
