CRCGN014_HEPG2_3H:B06 Gene Set
Genes
41 genes differentially expressed following the CRCGN014_HEPG2_3H:B06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
6.65586
|
|
HMOX1
|
heme oxygenase 1
|
5.93883
|
|
MAP7
|
microtubule-associated protein 7
|
5.73758
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.65192
|
|
TXNRD1
|
thioredoxin reductase 1
|
3.97069
|
|
IDE
|
insulin-degrading enzyme
|
3.89749
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
3.66674
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.52467
|
|
CCNA1
|
cyclin A1
|
3.41026
|
|
ABHD4
|
abhydrolase domain containing 4
|
3.16965
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.05009
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.93222
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.80834
|
|
CRTAP
|
cartilage associated protein
|
2.78288
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
2.72722
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.71454
|
|
SLC27A3
|
solute carrier family 27 (fatty acid transporter), member 3
|
2.68388
|
|
CGRRF1
|
cell growth regulator with ring finger domain 1
|
2.50721
|
|
C5
|
complement component 5
|
2.24075
|
|
RAP1GAP
|
RAP1 GTPase activating protein
|
2.16982
|
|
FOSL1
|
FOS-like antigen 1
|
2.07625
|
|
SNX7
|
sorting nexin 7
|
2.06765
|
|
CSK
|
c-src tyrosine kinase
|
2.04944
|
|
RFNG
|
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
|
2.0108
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-9.18691
|
|
COG2
|
component of oligomeric golgi complex 2
|
-4.94657
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-3.74966
|
|
DNTTIP2
|
deoxynucleotidyltransferase, terminal, interacting protein 2
|
-3.73858
|
|
PARP2
|
poly (ADP-ribose) polymerase 2
|
-3.34132
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.79231
|
|
TCEAL4
|
transcription elongation factor A (SII)-like 4
|
-2.75593
|
|
NFKBIA
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
|
-2.70167
|
|
WDR7
|
WD repeat domain 7
|
-2.65951
|
|
TBC1D31
|
TBC1 domain family, member 31
|
-2.59653
|
|
DENND2B
|
DENN domain containing 2B
|
-2.42058
|
|
RALA
|
v-ral simian leukemia viral oncogene homolog A (ras related)
|
-2.32018
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.18934
|
|
CDC20
|
cell division cycle 20
|
-2.16353
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.04544
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-2.01319
|
|
PIK3R4
|
phosphoinositide-3-kinase, regulatory subunit 4
|
-2.00951
|
