CRCGN014_HEPG2_3H:B09 Gene Set
Genes
54 genes differentially expressed following the CRCGN014_HEPG2_3H:B09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CGRRF1
|
cell growth regulator with ring finger domain 1
|
5.64421
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
4.53927
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
4.31108
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
4.0102
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.9477
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.79026
|
|
JADE2
|
jade family PHD finger 2
|
3.70054
|
|
ATP11B
|
ATPase, class VI, type 11B
|
3.53219
|
|
NPDC1
|
neural proliferation, differentiation and control, 1
|
3.48953
|
|
ZBTB18
|
zinc finger and BTB domain containing 18
|
3.06347
|
|
GRB10
|
growth factor receptor-bound protein 10
|
2.89284
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
2.8005
|
|
HPRT1
|
hypoxanthine phosphoribosyltransferase 1
|
2.51108
|
|
CDK19
|
cyclin-dependent kinase 19
|
2.48068
|
|
EPHA3
|
EPH receptor A3
|
2.47376
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
2.41674
|
|
TIPRL
|
TOR signaling pathway regulator
|
2.30609
|
|
WBP1L
|
WW domain binding protein 1-like
|
2.20568
|
|
MYLK
|
myosin light chain kinase
|
2.08248
|
|
HACD2
|
3-hydroxyacyl-CoA dehydratase 2
|
2.05865
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
2.02008
|
|
WDTC1
|
WD and tetratricopeptide repeats 1
|
2.01934
|
|
FLVCR2
|
feline leukemia virus subgroup C cellular receptor family, member 2
|
2.00193
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-10.0
|
|
DNM1L
|
dynamin 1-like
|
-7.31089
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-5.75042
|
|
CD320
|
CD320 molecule
|
-5.38998
|
|
ABL1
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
-5.27402
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-4.9465
|
|
LAP3
|
leucine aminopeptidase 3
|
-4.36409
|
|
CCNB2
|
cyclin B2
|
-4.34786
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
-4.12068
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.03099
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-2.91907
|
|
GRWD1
|
glutamate-rich WD repeat containing 1
|
-2.71199
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-2.54274
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.53665
|
|
YARS2
|
tyrosyl-tRNA synthetase 2, mitochondrial
|
-2.47822
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.46445
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.43696
|
|
PTCD3
|
pentatricopeptide repeat domain 3
|
-2.39844
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.33207
|
|
EXOC1
|
exocyst complex component 1
|
-2.26258
|
|
RBM28
|
RNA binding motif protein 28
|
-2.21206
|
|
H2AJ
|
H2A.J histone
|
-2.21115
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.10263
|
|
GAK
|
cyclin G associated kinase
|
-2.09864
|
|
DRAP1
|
DR1-associated protein 1 (negative cofactor 2 alpha)
|
-2.09628
|
|
FABP5
|
fatty acid binding protein 5 (psoriasis-associated)
|
-2.08485
|
|
ZNF586
|
zinc finger protein 586
|
-2.06791
|
|
TRIB3
|
tribbles pseudokinase 3
|
-2.05157
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.03721
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-2.03231
|
|
PSMD10
|
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
|
-2.02176
|
