CRCGN014_HEPG2_3H:B11 Gene Set
Genes
46 genes differentially expressed following the CRCGN014_HEPG2_3H:B11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
TXNRD1
|
thioredoxin reductase 1
|
4.76752
|
|
MAP7
|
microtubule-associated protein 7
|
4.3469
|
|
KEAP1
|
kelch-like ECH-associated protein 1
|
4.19406
|
|
SFTPB
|
surfactant protein B
|
3.85983
|
|
UBQLN2
|
ubiquilin 2
|
3.78744
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.72971
|
|
ABHD4
|
abhydrolase domain containing 4
|
3.56556
|
|
TIMM22
|
translocase of inner mitochondrial membrane 22 homolog (yeast)
|
3.40498
|
|
SLC35A1
|
solute carrier family 35 (CMP-sialic acid transporter), member A1
|
3.34924
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
3.34424
|
|
MINDY1
|
MINDY lysine 48 deubiquitinase 1
|
3.15333
|
|
STIMATE
|
STIM activating enhancer
|
3.13318
|
|
STK10
|
serine/threonine kinase 10
|
3.08539
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.99549
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
2.96183
|
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
2.95667
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.72237
|
|
KLHL9
|
kelch-like family member 9
|
2.39468
|
|
ABCB6
|
ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
|
2.29498
|
|
RFNG
|
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
|
2.19767
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.1682
|
|
COPS7A
|
COP9 signalosome subunit 7A
|
2.07685
|
|
BMPR1A
|
bone morphogenetic protein receptor, type IA
|
2.01526
|
|
TLK2
|
tousled-like kinase 2
|
2.0015
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-10.0
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-6.37324
|
|
PCNA
|
proliferating cell nuclear antigen
|
-6.19482
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-4.03555
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.64546
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.23327
|
|
PLD2
|
phospholipase D2
|
-2.89247
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.80735
|
|
LYPLA1
|
lysophospholipase I
|
-2.73062
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-2.67525
|
|
RNF167
|
ring finger protein 167
|
-2.64123
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.6316
|
|
WASHC4
|
WASH complex subunit 4
|
-2.5723
|
|
CSK
|
c-src tyrosine kinase
|
-2.51063
|
|
KANK3
|
KN motif and ankyrin repeat domains 3
|
-2.39022
|
|
ARHGDIB
|
Rho GDP dissociation inhibitor (GDI) beta
|
-2.36792
|
|
VPS35
|
vacuolar protein sorting 35 homolog (S. cerevisiae)
|
-2.33866
|
|
MRPL16
|
mitochondrial ribosomal protein L16
|
-2.23809
|
|
CCNB2
|
cyclin B2
|
-2.16299
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.15341
|
|
COX6B1
|
cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)
|
-2.09587
|
|
NFKBIA
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
|
-2.02845
|
