| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | phenformin 39.8 um perturbation at 3 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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72 genes differentially expressed following the CRCGN014_HEPG2_3H:B14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GSTZ1 | glutathione S-transferase zeta 1 | 5.67426 |
| EGR1 | early growth response 1 | 5.45921 |
| SCRN1 | secernin 1 | 5.27836 |
| CNPY3 | canopy FGF signaling regulator 3 | 5.05033 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 4.19681 |
| IER3 | immediate early response 3 | 3.98827 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 3.98728 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 3.92955 |
| PNKP | polynucleotide kinase 3'-phosphatase | 3.68279 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 3.61962 |
| PRR15L | proline rich 15-like | 3.56581 |
| AMDHD2 | amidohydrolase domain containing 2 | 3.51275 |
| ZFP36 | ZFP36 ring finger protein | 3.28399 |
| RPL39L | ribosomal protein L39-like | 3.20847 |
| CCP110 | centriolar coiled coil protein 110kDa | 3.20307 |
| ABHD4 | abhydrolase domain containing 4 | 3.20048 |
| KIFBP | kinesin family binding protein | 3.08336 |
| CYCS | cytochrome c, somatic | 2.8738 |
| CHN1 | chimerin 1 | 2.71034 |
| TRIB1 | tribbles pseudokinase 1 | 2.57624 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 2.56733 |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) | 2.48425 |
| UBQLN2 | ubiquilin 2 | 2.45296 |
| PLSCR1 | phospholipid scramblase 1 | 2.29975 |
| TBP | TATA box binding protein | 2.25038 |
| APIP | APAF1 interacting protein | 2.23853 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | 2.22008 |
| BCL10 | B-cell CLL/lymphoma 10 | 2.10894 |
| TEX10 | testis expressed 10 | 2.06641 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 2.04785 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 2.03761 |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 | 2.03261 |
| KLHL21 | kelch-like family member 21 | 2.01762 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FASTKD5 | FAST kinase domains 5 | -9.93824 |
| LDHD | lactate dehydrogenase D | -7.36644 |
| CCNB1 | cyclin B1 | -7.13669 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -6.78553 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -5.92064 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -4.94962 |
| GNAS | GNAS complex locus | -4.70894 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -4.67407 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -4.41736 |
| SLC35F2 | solute carrier family 35, member F2 | -4.35035 |
| DNM1L | dynamin 1-like | -4.34841 |
| FAIM | Fas apoptotic inhibitory molecule | -3.88509 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -3.62954 |
| NRIP1 | nuclear receptor interacting protein 1 | -3.55594 |
| LOC124907782 | dual specificity protein phosphatase 22 | -3.51817 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -3.46819 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.20539 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -3.07238 |
| KDM3A | lysine (K)-specific demethylase 3A | -2.93924 |
| GRWD1 | glutamate-rich WD repeat containing 1 | -2.90112 |
| HAT1 | histone acetyltransferase 1 | -2.86036 |
| MRPS2 | mitochondrial ribosomal protein S2 | -2.80096 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -2.64944 |
| HSPB1 | heat shock 27kDa protein 1 | -2.53992 |
| VAT1 | vesicle amine transport 1 | -2.21346 |
| TXNL4B | thioredoxin-like 4B | -2.19041 |
| SP140L | SP140 nuclear body protein-like | -2.13477 |
| HMOX1 | heme oxygenase 1 | -2.08831 |
| SCNN1B | sodium channel, non voltage gated 1 beta subunit | -2.08799 |
| H2AZ1 | H2A.Z variant histone 1 | -2.08011 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | -2.07754 |
| NVL | nuclear VCP-like | -2.07205 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | -2.04517 |
| HSPA8 | heat shock 70kDa protein 8 | -2.03375 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -2.03149 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.02997 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | -2.02327 |
| EPHA5 | EPH receptor A5 | -2.02224 |
| ZNF586 | zinc finger protein 586 | -2.00771 |
