| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 4,4'-oxydianiline 40.4 um perturbation at 3 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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52 genes differentially expressed following the CRCGN014_HEPG2_3H:B15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 7.09466 |
| GSTZ1 | glutathione S-transferase zeta 1 | 6.04133 |
| MAP7 | microtubule-associated protein 7 | 5.26398 |
| UBQLN2 | ubiquilin 2 | 4.92755 |
| CBR3 | carbonyl reductase 3 | 4.848 |
| CSK | c-src tyrosine kinase | 3.20583 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 3.10738 |
| KIF20A | kinesin family member 20A | 3.02769 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.91424 |
| KLHL9 | kelch-like family member 9 | 2.89147 |
| STXBP2 | syntaxin binding protein 2 | 2.88606 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.74417 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.72978 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 2.7187 |
| PNKP | polynucleotide kinase 3'-phosphatase | 2.71763 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 2.67981 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 2.55398 |
| TBP | TATA box binding protein | 2.55192 |
| STIMATE | STIM activating enhancer | 2.42635 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.31613 |
| MEST | mesoderm specific transcript | 2.24205 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.13955 |
| EPHB2 | EPH receptor B2 | 2.10881 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | 2.06171 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -7.01024 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -6.96233 |
| COG7 | component of oligomeric golgi complex 7 | -5.91406 |
| COG2 | component of oligomeric golgi complex 2 | -4.96789 |
| CCDC86 | coiled-coil domain containing 86 | -4.89976 |
| PRPF4 | pre-mRNA processing factor 4 | -4.83108 |
| CCNB1 | cyclin B1 | -4.45926 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -2.86758 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -2.81803 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -2.50706 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -2.48968 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.38323 |
| TLR4 | toll-like receptor 4 | -2.3734 |
| PCNA | proliferating cell nuclear antigen | -2.37322 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -2.33671 |
| CA3 | carbonic anhydrase III | -2.26632 |
| SPAM1 | sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) | -2.20499 |
| TXNDC9 | thioredoxin domain containing 9 | -2.18216 |
| MYH1 | myosin, heavy chain 1, skeletal muscle, adult | -2.10614 |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) | -2.09751 |
| NDE1 | nudE neurodevelopment protein 1 | -2.08323 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.06126 |
| BIRC2 | baculoviral IAP repeat containing 2 | -2.04954 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -2.0332 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -2.01794 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | -2.00997 |
| MRTFB | myocardin related transcription factor B | -2.00912 |
| TGFB2 | transforming growth factor, beta 2 | -2.00637 |
