CRCGN014_HEPG2_3H:B16 Gene Set
Genes
56 genes differentially expressed following the CRCGN014_HEPG2_3H:B16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAMLD1
|
mastermind-like domain containing 1
|
4.0258
|
|
TXNRD1
|
thioredoxin reductase 1
|
3.94471
|
|
UBQLN2
|
ubiquilin 2
|
3.85125
|
|
CHN1
|
chimerin 1
|
3.73062
|
|
MOK
|
MOK protein kinase
|
3.7127
|
|
HMOX1
|
heme oxygenase 1
|
3.69824
|
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
3.64597
|
|
PMM2
|
phosphomannomutase 2
|
3.61907
|
|
SFTPB
|
surfactant protein B
|
3.37071
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.34919
|
|
UFM1
|
ubiquitin-fold modifier 1
|
3.23657
|
|
TBPL1
|
TBP-like 1
|
3.18022
|
|
CCP110
|
centriolar coiled coil protein 110kDa
|
3.17514
|
|
STIMATE
|
STIM activating enhancer
|
3.10914
|
|
NOTCH1
|
notch 1
|
3.0983
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
2.9733
|
|
FOSL1
|
FOS-like antigen 1
|
2.89981
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.80995
|
|
ABHD4
|
abhydrolase domain containing 4
|
2.70919
|
|
MYLK
|
myosin light chain kinase
|
2.68864
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.65918
|
|
MYC
|
v-myc avian myelocytomatosis viral oncogene homolog
|
2.65353
|
|
RPS6KA1
|
ribosomal protein S6 kinase, 90kDa, polypeptide 1
|
2.62134
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.57414
|
|
KEAP1
|
kelch-like ECH-associated protein 1
|
2.47163
|
|
PRKCH
|
protein kinase C, eta
|
2.46632
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
2.37483
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.36902
|
|
IER3
|
immediate early response 3
|
2.21495
|
|
NCOA3
|
nuclear receptor coactivator 3
|
2.06979
|
|
TRIB3
|
tribbles pseudokinase 3
|
2.02999
|
|
KLHL21
|
kelch-like family member 21
|
2.01136
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CD320
|
CD320 molecule
|
-6.92203
|
|
LDHD
|
lactate dehydrogenase D
|
-6.49753
|
|
ZNF586
|
zinc finger protein 586
|
-6.19444
|
|
TLCD3A
|
TLC domain containing 3A
|
-5.07372
|
|
CDC20
|
cell division cycle 20
|
-4.83114
|
|
PSRC1
|
proline/serine-rich coiled-coil 1
|
-3.98425
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.60612
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-3.5177
|
|
TCEAL4
|
transcription elongation factor A (SII)-like 4
|
-3.44052
|
|
GNAS
|
GNAS complex locus
|
-2.77307
|
|
CCNB2
|
cyclin B2
|
-2.72829
|
|
SCCPDH
|
saccharopine dehydrogenase (putative)
|
-2.55845
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
-2.48528
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.445
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-2.39548
|
|
FABP5
|
fatty acid binding protein 5 (psoriasis-associated)
|
-2.32111
|
|
PCK2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
-2.30291
|
|
HAAO
|
3-hydroxyanthranilate 3,4-dioxygenase
|
-2.27001
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
-2.24796
|
|
HSPA8
|
heat shock 70kDa protein 8
|
-2.22598
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.19514
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-2.13368
|
|
YME1L1
|
YME1-like 1 ATPase
|
-2.05115
|
|
STAMBP
|
STAM binding protein
|
-2.03343
|
