CRCGN014_HEPG2_3H:B18 Gene Set
Genes
57 genes differentially expressed following the CRCGN014_HEPG2_3H:B18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
6.3539
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
4.06726
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
3.73995
|
|
RPL39L
|
ribosomal protein L39-like
|
3.36027
|
|
MYLK
|
myosin light chain kinase
|
3.32832
|
|
SKIC8
|
SKI8 subunit of superkiller complex
|
3.31929
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
3.21557
|
|
HDGFL3
|
HDGF like 3
|
3.21313
|
|
CHN1
|
chimerin 1
|
2.99352
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.98518
|
|
HOXA10
|
homeobox A10
|
2.88018
|
|
MINDY1
|
MINDY lysine 48 deubiquitinase 1
|
2.81748
|
|
TNIP1
|
TNFAIP3 interacting protein 1
|
2.80457
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
2.7713
|
|
AGL
|
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
|
2.75143
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.69859
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
2.60323
|
|
MAP7
|
microtubule-associated protein 7
|
2.59672
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.37372
|
|
TBP
|
TATA box binding protein
|
2.34879
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.29493
|
|
MEF2C
|
myocyte enhancer factor 2C
|
2.27374
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.22015
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.17443
|
|
WDTC1
|
WD and tetratricopeptide repeats 1
|
2.15261
|
|
MACROH2A2
|
macroH2A.2 histone
|
2.14624
|
|
FOXO3
|
forkhead box O3
|
2.03433
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
2.023
|
|
LUM
|
lumican
|
2.00827
|
|
TIMM22
|
translocase of inner mitochondrial membrane 22 homolog (yeast)
|
2.00234
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-9.44269
|
|
TUBB6
|
tubulin, beta 6 class V
|
-4.73192
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.20395
|
|
DNM1L
|
dynamin 1-like
|
-4.0192
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.86511
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-3.77212
|
|
ZNF586
|
zinc finger protein 586
|
-3.56277
|
|
CD320
|
CD320 molecule
|
-3.51125
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.49228
|
|
CCDC86
|
coiled-coil domain containing 86
|
-3.44151
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.42196
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-3.31543
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-3.30018
|
|
DUSP6
|
dual specificity phosphatase 6
|
-3.17299
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.04918
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-2.9146
|
|
SCAND1
|
SCAN domain containing 1
|
-2.72964
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.72743
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.72527
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-2.72131
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.64537
|
|
PEG10
|
paternally expressed 10
|
-2.49216
|
|
HSPA8
|
heat shock 70kDa protein 8
|
-2.45962
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.40239
|
|
IP6K2
|
inositol hexakisphosphate kinase 2
|
-2.08329
|
|
TBC1D8
|
TBC1 domain family, member 8 (with GRAM domain)
|
-2.04028
|
|
CCNB1
|
cyclin B1
|
-2.02407
|
