CRCGN014_HEPG2_3H:B20 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description ethinyl estradiol 39.8 um perturbation at 3 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

39 genes differentially expressed following the CRCGN014_HEPG2_3H:B20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 4.47763
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 4.07083
DENND2D DENN/MADD domain containing 2D 3.8878
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.828
TREM1 triggering receptor expressed on myeloid cells 1 3.5641
STIMATE STIM activating enhancer 3.24558
GPATCH8 G patch domain containing 8 3.05872
SFTPB surfactant protein B 3.00865
KIF20A kinesin family member 20A 2.82484
USP6NL USP6 N-terminal like 2.51655
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 2.4744
NOTCH1 notch 1 2.41322
H2BC12 H2B clustered histone 12 2.36335
ALAS1 5'-aminolevulinate synthase 1 2.13947
WFS1 Wolfram syndrome 1 (wolframin) 2.021
PRR15L proline rich 15-like 2.01191
CXCL2 chemokine (C-X-C motif) ligand 2 2.00905

decreased expression

Symbol Name Standardized Value
GOLT1B golgi transport 1B -3.85668
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -3.66601
TUBB6 tubulin, beta 6 class V -3.60065
CCNB2 cyclin B2 -3.55004
DERA deoxyribose-phosphate aldolase (putative) -3.40313
TLR4 toll-like receptor 4 -3.40164
ARID5B AT rich interactive domain 5B (MRF1-like) -3.31276
LDHD lactate dehydrogenase D -3.29871
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -3.12795
AZGP1 alpha-2-glycoprotein 1, zinc-binding -3.03675
ZMIZ1 zinc finger, MIZ-type containing 1 -3.00801
MAPK13 mitogen-activated protein kinase 13 -2.93601
ZNF586 zinc finger protein 586 -2.74328
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -2.70851
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.55758
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.52349
GTPBP8 GTP-binding protein 8 (putative) -2.23909
GDF15 growth differentiation factor 15 -2.20488
CSNK1E casein kinase 1, epsilon -2.12819
EGF epidermal growth factor -2.04064
NUSAP1 nucleolar and spindle associated protein 1 -2.03026
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -2.02755