CRCGN014_HEPG2_3H:B21 Gene Set
Genes
52 genes differentially expressed following the CRCGN014_HEPG2_3H:B21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
6.63067
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
6.37463
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
4.5825
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
4.07523
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.0273
|
|
ETS1
|
v-ets avian erythroblastosis virus E26 oncogene homolog 1
|
3.43463
|
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
3.30068
|
|
MAMLD1
|
mastermind-like domain containing 1
|
3.03153
|
|
LOC122526780
|
uncharacterized LOC122526780
|
3.02377
|
|
HYOU1
|
hypoxia up-regulated 1
|
2.91707
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
2.91567
|
|
MX1
|
MX dynamin-like GTPase 1
|
2.87087
|
|
NOTCH1
|
notch 1
|
2.75987
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.71547
|
|
MAP7
|
microtubule-associated protein 7
|
2.6069
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
2.49813
|
|
MICALL1
|
MICAL-like 1
|
2.4954
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.48757
|
|
ISG15
|
ISG15 ubiquitin-like modifier
|
2.36517
|
|
DDX60
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
|
2.35657
|
|
EPN2
|
epsin 2
|
2.28953
|
|
CPOX
|
coproporphyrinogen oxidase
|
2.24937
|
|
RAB21
|
RAB21, member RAS oncogene family
|
2.21817
|
|
GFOD1
|
glucose-fructose oxidoreductase domain containing 1
|
2.19957
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.13638
|
|
MYO5A
|
myosin VA (heavy chain 12, myoxin)
|
2.09113
|
|
AREL1
|
apoptosis resistant E3 ubiquitin protein ligase 1
|
2.0155
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TLR4
|
toll-like receptor 4
|
-5.94277
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-3.90987
|
|
PLK1
|
polo-like kinase 1
|
-3.72677
|
|
CD320
|
CD320 molecule
|
-3.57877
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.54053
|
|
VAT1
|
vesicle amine transport 1
|
-3.3853
|
|
THAP11
|
THAP domain containing 11
|
-3.32827
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-3.2283
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-3.17167
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.11793
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.11647
|
|
ZNF586
|
zinc finger protein 586
|
-3.10227
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-3.05627
|
|
IFRD2
|
interferon-related developmental regulator 2
|
-3.05458
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-2.927
|
|
TSPAN4
|
tetraspanin 4
|
-2.92323
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.86887
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.78352
|
|
GNAS
|
GNAS complex locus
|
-2.60083
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.5785
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.35858
|
|
SNX11
|
sorting nexin 11
|
-2.30338
|
|
SLC1A4
|
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
|
-2.17276
|
|
CD58
|
CD58 molecule
|
-2.08114
|
|
PSMD10
|
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
|
-2.04543
|
