CRCGN014_HEPG2_3H:B23 Gene Set
Genes
41 genes differentially expressed following the CRCGN014_HEPG2_3H:B23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
8.92967
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
5.6542
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.87633
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
4.85925
|
|
EPHB2
|
EPH receptor B2
|
4.8186
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
3.29896
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
3.09128
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.06182
|
|
MAP7
|
microtubule-associated protein 7
|
2.86396
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.85699
|
|
GATA3
|
GATA binding protein 3
|
2.84118
|
|
CYCS
|
cytochrome c, somatic
|
2.84092
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.66149
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
2.60505
|
|
UBR7
|
ubiquitin protein ligase E3 component n-recognin 7 (putative)
|
2.58652
|
|
SAA2
|
serum amyloid A2
|
2.57183
|
|
PLA2G2A
|
phospholipase A2, group IIA (platelets, synovial fluid)
|
2.48634
|
|
KIF20A
|
kinesin family member 20A
|
2.46361
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
2.4502
|
|
ICAM1
|
intercellular adhesion molecule 1
|
2.35144
|
|
SFTPB
|
surfactant protein B
|
2.35143
|
|
CCNF
|
cyclin F
|
2.33888
|
|
CSF3
|
colony stimulating factor 3 (granulocyte)
|
2.30949
|
|
CXCL3
|
chemokine (C-X-C motif) ligand 3
|
2.03387
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-5.62278
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.5969
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-4.56305
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-4.03656
|
|
CCNB2
|
cyclin B2
|
-3.71297
|
|
ZNF586
|
zinc finger protein 586
|
-3.68973
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.64953
|
|
RAI14
|
retinoic acid induced 14
|
-3.46734
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.22649
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-3.21834
|
|
CDC25B
|
cell division cycle 25B
|
-2.53351
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
-2.46104
|
|
CSK
|
c-src tyrosine kinase
|
-2.39867
|
|
DCK
|
deoxycytidine kinase
|
-2.29977
|
|
DNAJC15
|
DnaJ (Hsp40) homolog, subfamily C, member 15
|
-2.27163
|
|
HMGCR
|
3-hydroxy-3-methylglutaryl-CoA reductase
|
-2.1423
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.11091
|
