CRCGN014_HEPG2_3H:C01 Gene Set
Genes
55 genes differentially expressed following the CRCGN014_HEPG2_3H:C01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
6.04511
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
6.02262
|
|
HOXA10
|
homeobox A10
|
5.17646
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
4.6377
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
4.51129
|
|
PMM2
|
phosphomannomutase 2
|
4.05365
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
4.00136
|
|
CBR3
|
carbonyl reductase 3
|
3.99511
|
|
TIMM22
|
translocase of inner mitochondrial membrane 22 homolog (yeast)
|
3.9883
|
|
GPATCH8
|
G patch domain containing 8
|
3.8647
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.76159
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
3.53317
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
3.38701
|
|
STK10
|
serine/threonine kinase 10
|
3.33178
|
|
HYOU1
|
hypoxia up-regulated 1
|
3.22687
|
|
ABHD6
|
abhydrolase domain containing 6
|
3.10238
|
|
ARID4B
|
AT rich interactive domain 4B (RBP1-like)
|
3.04695
|
|
EPN2
|
epsin 2
|
3.04161
|
|
HOXA10-HOXA9
|
HOXA10-HOXA9 readthrough
|
2.94102
|
|
CSK
|
c-src tyrosine kinase
|
2.85992
|
|
ATP11B
|
ATPase, class VI, type 11B
|
2.79546
|
|
MYLK
|
myosin light chain kinase
|
2.78646
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.69711
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.67292
|
|
CYCS
|
cytochrome c, somatic
|
2.57938
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
2.56904
|
|
HOXA11
|
homeobox A11
|
2.52015
|
|
RAP1GAP
|
RAP1 GTPase activating protein
|
2.47387
|
|
STXBP2
|
syntaxin binding protein 2
|
2.44173
|
|
SHISAL1
|
shisa like 1
|
2.17809
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.16471
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.01018
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-5.75436
|
|
CCNB1
|
cyclin B1
|
-5.70993
|
|
TLR4
|
toll-like receptor 4
|
-5.14165
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.90466
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.76444
|
|
CCNB2
|
cyclin B2
|
-3.64218
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-3.5795
|
|
COG7
|
component of oligomeric golgi complex 7
|
-3.56739
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.13089
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.77489
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.67255
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.66236
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
-2.46713
|
|
ZNF274
|
zinc finger protein 274
|
-2.29836
|
|
TRIB3
|
tribbles pseudokinase 3
|
-2.28659
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-2.16011
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.14955
|
|
SCCPDH
|
saccharopine dehydrogenase (putative)
|
-2.13297
|
|
GALE
|
UDP-galactose-4-epimerase
|
-2.12438
|
|
GATC
|
glutamyl-tRNA(Gln) amidotransferase, subunit C
|
-2.09592
|
|
COPS7A
|
COP9 signalosome subunit 7A
|
-2.08347
|
|
GTF2H5
|
general transcription factor IIH, polypeptide 5
|
-2.02351
|
|
GET1
|
guided entry of tail-anchored proteins factor 1
|
-2.01143
|
