| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 1,1,1-trichloroethane, technical grade 39.0 um perturbation at 3 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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55 genes differentially expressed following the CRCGN014_HEPG2_3H:C05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GSTZ1 | glutathione S-transferase zeta 1 | 5.5428 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 5.22323 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 4.47287 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 4.46116 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.3988 |
| GATA3 | GATA binding protein 3 | 4.35164 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 3.88145 |
| CYCS | cytochrome c, somatic | 3.76304 |
| MAP7 | microtubule-associated protein 7 | 3.70508 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 3.30126 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 3.30124 |
| SCCPDH | saccharopine dehydrogenase (putative) | 2.85302 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 2.82996 |
| KIF14 | kinesin family member 14 | 2.65501 |
| EGF | epidermal growth factor | 2.40402 |
| NPY1R | neuropeptide Y receptor Y1 | 2.4016 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | 2.4015 |
| SAA2 | serum amyloid A2 | 2.38836 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 2.35699 |
| JADE2 | jade family PHD finger 2 | 2.32756 |
| NOTCH1 | notch 1 | 2.32306 |
| TSPAN6 | tetraspanin 6 | 2.31591 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 2.30154 |
| CPVL | carboxypeptidase, vitellogenic-like | 2.29007 |
| NOVA1 | neuro-oncological ventral antigen 1 | 2.20502 |
| CSK | c-src tyrosine kinase | 2.17336 |
| KLHL9 | kelch-like family member 9 | 2.11419 |
| WASF3 | WAS protein family, member 3 | 2.08056 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 2.07912 |
| MEST | mesoderm specific transcript | 2.05728 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | 2.04786 |
| HSD11B2 | hydroxysteroid (11-beta) dehydrogenase 2 | 2.03064 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DNM1L | dynamin 1-like | -5.23682 |
| ZNF586 | zinc finger protein 586 | -5.18812 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -5.11771 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -4.93097 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.57045 |
| CCNB2 | cyclin B2 | -4.30716 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.18228 |
| PRPF4 | pre-mRNA processing factor 4 | -4.11011 |
| TRIB3 | tribbles pseudokinase 3 | -4.09996 |
| WASHC4 | WASH complex subunit 4 | -3.94975 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -3.61541 |
| GNAS | GNAS complex locus | -3.43232 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.33143 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.94561 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -2.90526 |
| HSPA8 | heat shock 70kDa protein 8 | -2.4472 |
| YARS2 | tyrosyl-tRNA synthetase 2, mitochondrial | -2.273 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | -2.18733 |
| RPL35 | ribosomal protein L35 | -2.12134 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -2.12009 |
| CCNH | cyclin H | -2.0375 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -2.03552 |
| RPL10A | ribosomal protein L10a | -2.01254 |
