CRCGN014_HEPG2_3H:C09 Gene Set
Genes
41 genes differentially expressed following the CRCGN014_HEPG2_3H:C09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
7.68531
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
7.6459
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
6.60852
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
6.39449
|
|
GPATCH8
|
G patch domain containing 8
|
5.36196
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.79658
|
|
TIMM22
|
translocase of inner mitochondrial membrane 22 homolog (yeast)
|
3.79515
|
|
SKIC8
|
SKI8 subunit of superkiller complex
|
3.38344
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
3.2988
|
|
ATP11B
|
ATPase, class VI, type 11B
|
3.15242
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.99691
|
|
CYCS
|
cytochrome c, somatic
|
2.96001
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.74528
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.74405
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.49987
|
|
RRAGA
|
Ras-related GTP binding A
|
2.32042
|
|
ETS1
|
v-ets avian erythroblastosis virus E26 oncogene homolog 1
|
2.30367
|
|
FSD1
|
fibronectin type III and SPRY domain containing 1
|
2.13515
|
|
CHN1
|
chimerin 1
|
2.05449
|
|
TXNL4B
|
thioredoxin-like 4B
|
2.04944
|
|
IGFBP2
|
insulin-like growth factor binding protein 2, 36kDa
|
2.02819
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-10.0
|
|
ZNF586
|
zinc finger protein 586
|
-9.40367
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-6.13575
|
|
TLR4
|
toll-like receptor 4
|
-5.97986
|
|
CCNB2
|
cyclin B2
|
-5.33878
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.65657
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-4.38059
|
|
PLK1
|
polo-like kinase 1
|
-3.61228
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.41459
|
|
HMG20B
|
high mobility group 20B
|
-3.17467
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-3.16453
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.67696
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.55349
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-2.44008
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-2.34492
|
|
FKBP6
|
FK506 binding protein 6, 36kDa
|
-2.3302
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.31319
|
|
FOLR3
|
folate receptor 3 (gamma)
|
-2.25126
|
|
GNAS
|
GNAS complex locus
|
-2.22143
|
|
PIWIL1
|
piwi-like RNA-mediated gene silencing 1
|
-2.08331
|
