CRCGN014_HEPG2_3H:C12 Gene Set
Genes
49 genes differentially expressed following the CRCGN014_HEPG2_3H:C12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
10.0
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
5.25133
|
|
CYCS
|
cytochrome c, somatic
|
5.21695
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
4.91566
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
4.79085
|
|
CCNF
|
cyclin F
|
3.71058
|
|
NPDC1
|
neural proliferation, differentiation and control, 1
|
3.65118
|
|
ADGRG1
|
adhesion G protein-coupled receptor G1
|
3.02222
|
|
UBQLN2
|
ubiquilin 2
|
2.95434
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
2.91563
|
|
TEX10
|
testis expressed 10
|
2.64954
|
|
ZNF589
|
zinc finger protein 589
|
2.63928
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
2.60022
|
|
BTK
|
Bruton agammaglobulinemia tyrosine kinase
|
2.54376
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.43427
|
|
PLIN1
|
perilipin 1
|
2.34226
|
|
NOTCH1
|
notch 1
|
2.26816
|
|
TAX1BP1
|
Tax1 (human T-cell leukemia virus type I) binding protein 1
|
2.22426
|
|
EGR1
|
early growth response 1
|
2.18887
|
|
ITIH5
|
inter-alpha-trypsin inhibitor heavy chain family, member 5
|
2.14687
|
|
ADIPOQ
|
adiponectin, C1Q and collagen domain containing
|
2.12714
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.11859
|
|
H2BC12
|
H2B clustered histone 12
|
2.10362
|
|
ALOX15B
|
arachidonate 15-lipoxygenase, type B
|
2.08924
|
|
EDEM1
|
ER degradation enhancer, mannosidase alpha-like 1
|
2.03183
|
|
PPP1R14D
|
protein phosphatase 1, regulatory (inhibitor) subunit 14D
|
2.01749
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.01275
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-7.10204
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-5.07525
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.91489
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.53084
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-3.93823
|
|
WASHC4
|
WASH complex subunit 4
|
-3.87762
|
|
GNAS
|
GNAS complex locus
|
-3.59464
|
|
VAT1
|
vesicle amine transport 1
|
-3.54227
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-3.37998
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-3.33707
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-3.14297
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.10417
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-2.97139
|
|
HSPA8
|
heat shock 70kDa protein 8
|
-2.95982
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.90966
|
|
TXNRD1
|
thioredoxin reductase 1
|
-2.7408
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.55439
|
|
ICAM3
|
intercellular adhesion molecule 3
|
-2.42306
|
|
NAA16
|
N(alpha)-acetyltransferase 16, NatA auxiliary subunit
|
-2.23502
|
|
SPG21
|
spastic paraplegia 21 (autosomal recessive, Mast syndrome)
|
-2.10763
|
|
MTERF3
|
mitochondrial transcription termination factor 3
|
-2.05302
|
|
SOAT2
|
sterol O-acyltransferase 2
|
-2.01065
|
