CRCGN014_HEPG2_3H:C13 Gene Set
Genes
44 genes differentially expressed following the CRCGN014_HEPG2_3H:C13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
6.57919
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
5.287
|
|
UBQLN2
|
ubiquilin 2
|
3.90483
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
3.779
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
3.64232
|
|
MAMLD1
|
mastermind-like domain containing 1
|
3.56914
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
3.2124
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.12933
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
3.08197
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
2.97081
|
|
MNAT1
|
MNAT CDK-activating kinase assembly factor 1
|
2.91403
|
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
2.77269
|
|
LCN2
|
lipocalin 2
|
2.72841
|
|
STXBP2
|
syntaxin binding protein 2
|
2.70921
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.4857
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.42469
|
|
MMP1
|
matrix metallopeptidase 1
|
2.37366
|
|
COQ8A
|
coenzyme Q8A
|
2.27377
|
|
EPHA3
|
EPH receptor A3
|
2.2275
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.04073
|
|
ADAM10
|
ADAM metallopeptidase domain 10
|
2.02144
|
|
CSK
|
c-src tyrosine kinase
|
2.01462
|
|
BAMBI
|
BMP and activin membrane-bound inhibitor
|
2.00846
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
DNM1L
|
dynamin 1-like
|
-4.17805
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.87256
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.73626
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.43981
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-3.23218
|
|
YME1L1
|
YME1-like 1 ATPase
|
-3.00091
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.78135
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-2.68448
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.64551
|
|
HSPA8
|
heat shock 70kDa protein 8
|
-2.58251
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.57174
|
|
RND1
|
Rho family GTPase 1
|
-2.52578
|
|
ZNF586
|
zinc finger protein 586
|
-2.34529
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.27056
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.2615
|
|
TBX2
|
T-box 2
|
-2.24975
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.23566
|
|
ILF2
|
interleukin enhancer binding factor 2
|
-2.16349
|
|
CD320
|
CD320 molecule
|
-2.07141
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.05082
|
|
POLG2
|
polymerase (DNA directed), gamma 2, accessory subunit
|
-2.04567
|
