| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 3-(p-chlorophenyl)-1,1-di?methyl?urea 39.4 um perturbation at 3 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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58 genes differentially expressed following the CRCGN014_HEPG2_3H:C18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPARG | peroxisome proliferator-activated receptor gamma | 7.66342 |
| GPER1 | G protein-coupled estrogen receptor 1 | 5.97359 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 4.93921 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.93453 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 4.86786 |
| PRR15L | proline rich 15-like | 4.21989 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.15185 |
| MAP7 | microtubule-associated protein 7 | 3.99634 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 3.73009 |
| CEP57 | centrosomal protein 57kDa | 3.25452 |
| CHN1 | chimerin 1 | 3.08623 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.04856 |
| UBQLN2 | ubiquilin 2 | 2.95006 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 2.86778 |
| GPATCH8 | G patch domain containing 8 | 2.85012 |
| ABHD6 | abhydrolase domain containing 6 | 2.79179 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 2.7228 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 2.56147 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 2.55442 |
| KIF14 | kinesin family member 14 | 2.52894 |
| CCL2 | chemokine (C-C motif) ligand 2 | 2.505 |
| HYOU1 | hypoxia up-regulated 1 | 2.47747 |
| MSRA | methionine sulfoxide reductase A | 2.44858 |
| STK10 | serine/threonine kinase 10 | 2.44635 |
| CCNF | cyclin F | 2.31141 |
| TEDC2 | tubulin epsilon and delta complex 2 | 2.29586 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.20251 |
| MOK | MOK protein kinase | 2.16224 |
| RAMP3 | receptor (G protein-coupled) activity modifying protein 3 | 2.1604 |
| ETFDH | electron-transferring-flavoprotein dehydrogenase | 2.1258 |
| CDC45 | cell division cycle 45 | 2.0136 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.0011 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ADI1 | acireductone dioxygenase 1 | -5.48088 |
| HSPB1 | heat shock 27kDa protein 1 | -5.30023 |
| PCNA | proliferating cell nuclear antigen | -4.8063 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.20171 |
| CCNB1 | cyclin B1 | -3.70786 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.68068 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -3.52324 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -3.5156 |
| GNAS | GNAS complex locus | -3.44355 |
| NUP85 | nucleoporin 85kDa | -3.18429 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -3.08993 |
| PRPF4 | pre-mRNA processing factor 4 | -2.98201 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -2.95161 |
| TXNDC9 | thioredoxin domain containing 9 | -2.87345 |
| MRPL58 | mitochondrial ribosomal protein L58 | -2.71112 |
| MRPS2 | mitochondrial ribosomal protein S2 | -2.51379 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -2.48772 |
| SUMO4 | small ubiquitin-like modifier 4 | -2.38882 |
| TXNRD1 | thioredoxin reductase 1 | -2.38573 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -2.31538 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -2.26002 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -2.25351 |
| HMOX1 | heme oxygenase 1 | -2.21132 |
| GRB2 | growth factor receptor-bound protein 2 | -2.1632 |
| WDR7 | WD repeat domain 7 | -2.1286 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.09527 |
