CRCGN014_HEPG2_3H:C19 Gene Set
Genes
48 genes differentially expressed following the CRCGN014_HEPG2_3H:C19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
5.30134
|
|
ATP11B
|
ATPase, class VI, type 11B
|
4.12753
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.98576
|
|
PLSCR3
|
phospholipid scramblase 3
|
3.11255
|
|
MOK
|
MOK protein kinase
|
3.11073
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.05423
|
|
NOTCH1
|
notch 1
|
2.98154
|
|
TESK1
|
testis-specific kinase 1
|
2.87522
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.77963
|
|
MEF2C
|
myocyte enhancer factor 2C
|
2.74796
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.71604
|
|
INTS3
|
integrator complex subunit 3
|
2.63189
|
|
SYNGAP1
|
synaptic Ras GTPase activating protein 1
|
2.5164
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
2.4824
|
|
EPHB2
|
EPH receptor B2
|
2.42798
|
|
SHC1
|
SHC (Src homology 2 domain containing) transforming protein 1
|
2.36631
|
|
STXBP2
|
syntaxin binding protein 2
|
2.292
|
|
CYCS
|
cytochrome c, somatic
|
2.26726
|
|
SFTPB
|
surfactant protein B
|
2.1815
|
|
CRIP2
|
cysteine-rich protein 2
|
2.17337
|
|
SMIM40
|
small integral membrane protein 40
|
2.14411
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.026
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.01441
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-9.09454
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.3469
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.03667
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-3.71905
|
|
CCDC86
|
coiled-coil domain containing 86
|
-3.52767
|
|
TLR4
|
toll-like receptor 4
|
-3.33893
|
|
GTPBP8
|
GTP-binding protein 8 (putative)
|
-3.24676
|
|
LDHD
|
lactate dehydrogenase D
|
-3.12072
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.07165
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.03526
|
|
CCNB2
|
cyclin B2
|
-3.0122
|
|
GOLT1B
|
golgi transport 1B
|
-2.91357
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.88374
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.6694
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.66037
|
|
SNX11
|
sorting nexin 11
|
-2.37558
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-2.36372
|
|
GFPT2
|
glutamine-fructose-6-phosphate transaminase 2
|
-2.27631
|
|
CCNB1
|
cyclin B1
|
-2.23492
|
|
ZNF134
|
zinc finger protein 134
|
-2.22352
|
|
HEATR1
|
HEAT repeat containing 1
|
-2.13105
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
-2.11262
|
|
DDX6
|
DEAD (Asp-Glu-Ala-Asp) box helicase 6
|
-2.06962
|
|
PIK3C2G
|
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma
|
-2.05098
|
|
EGF
|
epidermal growth factor
|
-2.03074
|
