CRCGN014_HEPG2_3H:C20 Gene Set
Genes
53 genes differentially expressed following the CRCGN014_HEPG2_3H:C20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ADRB2
|
adrenoceptor beta 2, surface
|
3.94835
|
|
PTK2
|
protein tyrosine kinase 2
|
3.13628
|
|
DHX29
|
DEAH (Asp-Glu-Ala-His) box polypeptide 29
|
3.04664
|
|
TGFBR2
|
transforming growth factor, beta receptor II (70/80kDa)
|
2.94064
|
|
NFIL3
|
nuclear factor, interleukin 3 regulated
|
2.82936
|
|
MSRA
|
methionine sulfoxide reductase A
|
2.81217
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.61268
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
2.59921
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.57183
|
|
MAP7
|
microtubule-associated protein 7
|
2.53227
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
2.48073
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.41115
|
|
PLS1
|
plastin 1
|
2.39449
|
|
CCNA1
|
cyclin A1
|
2.39304
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.30237
|
|
UBE2L6
|
ubiquitin-conjugating enzyme E2L 6
|
2.24119
|
|
TEX10
|
testis expressed 10
|
2.21724
|
|
E2F2
|
E2F transcription factor 2
|
2.17876
|
|
KIF14
|
kinesin family member 14
|
2.16649
|
|
ETS1
|
v-ets avian erythroblastosis virus E26 oncogene homolog 1
|
2.16534
|
|
CYCS
|
cytochrome c, somatic
|
2.15054
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.14491
|
|
FZD7
|
frizzled class receptor 7
|
2.14281
|
|
CHN1
|
chimerin 1
|
2.1264
|
|
GPATCH8
|
G patch domain containing 8
|
2.06819
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.05383
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
2.05193
|
|
BNC1
|
basonuclin 1
|
2.04461
|
|
CD40
|
CD40 molecule, TNF receptor superfamily member 5
|
2.01407
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
AKR7A2
|
aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)
|
-4.47964
|
|
RPS4Y1
|
ribosomal protein S4, Y-linked 1
|
-4.4392
|
|
NFKBIA
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
|
-4.22178
|
|
LDHD
|
lactate dehydrogenase D
|
-4.10352
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.99695
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.85777
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.64645
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.64511
|
|
ZNF586
|
zinc finger protein 586
|
-3.34033
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.20534
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-3.12579
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.01386
|
|
GNAS
|
GNAS complex locus
|
-2.78604
|
|
GLOD4
|
glyoxalase domain containing 4
|
-2.67429
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.62016
|
|
COG2
|
component of oligomeric golgi complex 2
|
-2.58975
|
|
RNF167
|
ring finger protein 167
|
-2.50042
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-2.38093
|
|
TLR4
|
toll-like receptor 4
|
-2.28909
|
|
TCTN1
|
tectonic family member 1
|
-2.24703
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.16675
|
|
AKR7A3
|
aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)
|
-2.156
|
|
BIRC2
|
baculoviral IAP repeat containing 2
|
-2.09786
|
|
TCFL5
|
transcription factor-like 5 (basic helix-loop-helix)
|
-2.07983
|
