CRCGN014_HEPG2_3H:C23 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description aramite 0.01 um perturbation at 3 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

56 genes differentially expressed following the CRCGN014_HEPG2_3H:C23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MOK MOK protein kinase 4.79203
MYLK myosin light chain kinase 4.57673
CXCL2 chemokine (C-X-C motif) ligand 2 4.53468
CIAO3 cytosolic iron-sulfur assembly component 3 4.51066
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 4.48749
TREM1 triggering receptor expressed on myeloid cells 1 4.10039
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 3.95419
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 3.53215
USP6NL USP6 N-terminal like 3.38372
SNAP25 synaptosomal-associated protein, 25kDa 3.25734
C5 complement component 5 3.07673
KIF20A kinesin family member 20A 3.02923
GSTZ1 glutathione S-transferase zeta 1 2.97872
CHN1 chimerin 1 2.94436
PPP1R13B protein phosphatase 1, regulatory subunit 13B 2.94351
CASP10 caspase 10, apoptosis-related cysteine peptidase 2.77679
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 2.76367
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) 2.60824
EPHA3 EPH receptor A3 2.57474
DIPK1A divergent protein kinase domain 1A 2.52079
ASIC2 acid sensing (proton gated) ion channel 2 2.52041
PCDHB11 protocadherin beta 11 2.40952
APOF apolipoprotein F 2.39171
IQSEC2 IQ motif and Sec7 domain 2 2.29915
TGFB1I1 transforming growth factor beta 1 induced transcript 1 2.23752
STK32B serine/threonine kinase 32B 2.23095
ART3 ADP-ribosyltransferase 3 2.19397
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.10697
KLHL3 kelch-like family member 3 2.08599
CCL20 chemokine (C-C motif) ligand 20 2.06506
FSD1 fibronectin type III and SPRY domain containing 1 2.06283
H2BC11 H2B clustered histone 11 2.0558
TDO2 tryptophan 2,3-dioxygenase 2.03795
CNPY3-GNMT CNPY3-GNMT readthrough 2.02992
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4 2.00875
AMPH amphiphysin 2.00821
CCDC85B coiled-coil domain containing 85B 2.00296

decreased expression

Symbol Name Standardized Value
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -5.32273
OXA1L oxidase (cytochrome c) assembly 1-like -5.08464
TARBP1 TAR (HIV-1) RNA binding protein 1 -4.77615
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -4.68141
VAT1 vesicle amine transport 1 -4.61203
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -4.49838
CCNB2 cyclin B2 -4.2525
CTSD cathepsin D -4.16807
FGFR4 fibroblast growth factor receptor 4 -3.68867
CASP7 caspase 7, apoptosis-related cysteine peptidase -3.59683
PRPF4 pre-mRNA processing factor 4 -3.40556
TXNDC9 thioredoxin domain containing 9 -3.07532
PARP2 poly (ADP-ribose) polymerase 2 -3.0015
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) -2.7225
CSK c-src tyrosine kinase -2.30752
HS6ST1 heparan sulfate 6-O-sulfotransferase 1 -2.08841
COXFA4L2 cytochrome c oxidase hypoxia associated subunit FA4L2 -2.05966
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha -2.0128
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) -2.00022