| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | pentachlorophenol 39.4 um perturbation at 3 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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140 genes differentially expressed following the CRCGN014_HEPG2_3H:D05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CHMP6 | charged multivesicular body protein 6 | 8.15585 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 6.34618 |
| GPATCH8 | G patch domain containing 8 | 6.03333 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 5.8439 |
| ADRB2 | adrenoceptor beta 2, surface | 5.5359 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 5.51575 |
| TAC4 | tachykinin 4 (hemokinin) | 5.5069 |
| UBQLN2 | ubiquilin 2 | 5.33325 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 5.076 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 5.03845 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.92235 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 4.9129 |
| HSPA1A | heat shock 70kDa protein 1A | 4.893 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 4.51685 |
| LPAR2 | lysophosphatidic acid receptor 2 | 4.22857 |
| HOXA10 | homeobox A10 | 4.0406 |
| MINDY1 | MINDY lysine 48 deubiquitinase 1 | 4.0108 |
| EPHB2 | EPH receptor B2 | 3.77084 |
| ILK | integrin-linked kinase | 3.6032 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 3.5357 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 3.4877 |
| BTK | Bruton agammaglobulinemia tyrosine kinase | 3.40135 |
| MCUR1 | mitochondrial calcium uniporter regulator 1 | 3.20575 |
| EVL | Enah/Vasp-like | 3.1733 |
| CYCS | cytochrome c, somatic | 3.1551 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 3.12788 |
| DDIT4 | DNA-damage-inducible transcript 4 | 3.1036 |
| MAP7 | microtubule-associated protein 7 | 3.06113 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 3.0482 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 2.9645 |
| NUP133 | nucleoporin 133kDa | 2.8261 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.82035 |
| LAGE3 | L antigen family, member 3 | 2.7633 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 2.5496 |
| LOC122526780 | uncharacterized LOC122526780 | 2.5392 |
| CEP57 | centrosomal protein 57kDa | 2.48133 |
| PF4 | platelet factor 4 | 2.4482 |
| MOK | MOK protein kinase | 2.4426 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 2.38735 |
| CBR3 | carbonyl reductase 3 | 2.3873 |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) | 2.3845 |
| STAP2 | signal transducing adaptor family member 2 | 2.3507 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 2.34037 |
| TBCC | tubulin folding cofactor C | 2.32485 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 2.28977 |
| SLC75A1 | solute carrier family 75 member 1 | 2.23935 |
| TP53I3 | tumor protein p53 inducible protein 3 | 2.21215 |
| NXF2B | nuclear RNA export factor 2B | 2.19128 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 2.18705 |
| SMNDC1 | survival motor neuron domain containing 1 | 2.1865 |
| GRIN2C | glutamate receptor, ionotropic, N-methyl D-aspartate 2C | 2.1822 |
| TRIM13 | tripartite motif containing 13 | 2.1804 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 2.16145 |
| LRIG3 | leucine-rich repeats and immunoglobulin-like domains 3 | 2.14115 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein | 2.13305 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.1139 |
| RBM7 | RNA binding motif protein 7 | 2.10685 |
| TMEM248 | transmembrane protein 248 | 2.104 |
| KIF20A | kinesin family member 20A | 2.0904 |
| ZNF562 | zinc finger protein 562 | 2.08485 |
| POLR1D | polymerase (RNA) I polypeptide D, 16kDa | 2.0804 |
| MAD2L1BP | MAD2L1 binding protein | 2.0777 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 2.0479 |
| AXIN1 | axin 1 | 2.0459 |
| CD9 | CD9 molecule | 2.04525 |
| CRMP1 | collapsin response mediator protein 1 | 2.04215 |
| ITGA10 | integrin, alpha 10 | 2.038 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 2.03592 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | 2.03272 |
| MDN1 | MDN1, midasin homolog (yeast) | 2.0193 |
| WDR46 | WD repeat domain 46 | 2.01645 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -5.0557 |
| VAT1 | vesicle amine transport 1 | -5.0 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.9861 |
| TBC1D31 | TBC1 domain family, member 31 | -4.7951 |
| LDHD | lactate dehydrogenase D | -4.66845 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -4.59955 |
| SLC35F2 | solute carrier family 35, member F2 | -4.516 |
| TLR4 | toll-like receptor 4 | -4.3273 |
| DCK | deoxycytidine kinase | -4.2404 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -4.09695 |
| SLC35B1 | solute carrier family 35, member B1 | -3.96745 |
| UBE3C | ubiquitin protein ligase E3C | -3.9211 |
| STMN1 | stathmin 1 | -3.70495 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.6475 |
| GNAS | GNAS complex locus | -3.61828 |
| PSRC1 | proline/serine-rich coiled-coil 1 | -3.50305 |
| TLCD3A | TLC domain containing 3A | -2.93555 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -2.92727 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.91205 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.778 |
| SLC25A1 | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 | -2.64265 |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase | -2.6363 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -2.53075 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | -2.47983 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -2.4576 |
| ZMYM6 | zinc finger, MYM-type 6 | -2.44 |
| ERH | enhancer of rudimentary homolog (Drosophila) | -2.4381 |
| WASF1 | WAS protein family, member 1 | -2.43675 |
| PKD2L2 | polycystic kidney disease 2-like 2 | -2.4362 |
| PSIP1 | PC4 and SFRS1 interacting protein 1 | -2.42128 |
| TATDN2 | TatD DNase domain containing 2 | -2.41495 |
| DGCR6L | DiGeorge syndrome critical region gene 6-like | -2.34195 |
| CBR1 | carbonyl reductase 1 | -2.3363 |
| WASHC4 | WASH complex subunit 4 | -2.30905 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | -2.30825 |
| MSH6 | mutS homolog 6 | -2.30107 |
| ABHD10 | abhydrolase domain containing 10 | -2.30055 |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 | -2.29105 |
| USP1 | ubiquitin specific peptidase 1 | -2.28982 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -2.2844 |
| SLCO5A1 | solute carrier organic anion transporter family, member 5A1 | -2.26495 |
| CYP46A1 | cytochrome P450, family 46, subfamily A, polypeptide 1 | -2.2375 |
| STXBP2 | syntaxin binding protein 2 | -2.22595 |
| PDHX | pyruvate dehydrogenase complex, component X | -2.20505 |
| DGKE | diacylglycerol kinase, epsilon 64kDa | -2.20435 |
| SMC6 | structural maintenance of chromosomes 6 | -2.2026 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -2.1971 |
| TRIM44 | tripartite motif containing 44 | -2.1727 |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) | -2.16 |
| MAGEB2 | melanoma antigen family B2 | -2.15695 |
| IREB2 | iron-responsive element binding protein 2 | -2.152 |
| ANO3 | anoctamin 3 | -2.1499 |
| BMP2K | BMP2 inducible kinase | -2.14821 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.1457 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -2.12495 |
| SLC67A2 | solute carrier family 67 member 2 | -2.12185 |
| ARRB2 | arrestin, beta 2 | -2.1212 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -2.10308 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -2.09748 |
| PDZD2 | PDZ domain containing 2 | -2.09453 |
| ADGB | androglobin | -2.08405 |
| QSER1 | glutamine and serine rich 1 | -2.0829 |
| THAP9 | THAP domain containing 9 | -2.07955 |
| CCDC181 | coiled-coil domain containing 181 | -2.0792 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -2.0601 |
| NRDC | nardilysin convertase | -2.031 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -2.02975 |
| CYB5R3 | cytochrome b5 reductase 3 | -2.02015 |
| DEFB126 | defensin, beta 126 | -2.01095 |
