| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 4,4'-methylene-bis(2-methyl?aniline) 40.0 um perturbation at 3 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
74 genes differentially expressed following the CRCGN014_HEPG2_3H:D09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 8.40655 |
| MYLK | myosin light chain kinase | 5.1296 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 5.12815 |
| CCNF | cyclin F | 5.09092 |
| LAGE3 | L antigen family, member 3 | 5.0 |
| TRAM2 | translocation associated membrane protein 2 | 4.00737 |
| SCRN1 | secernin 1 | 3.77035 |
| PLSCR1 | phospholipid scramblase 1 | 3.70108 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 3.6882 |
| DIPK1A | divergent protein kinase domain 1A | 3.58585 |
| CYCS | cytochrome c, somatic | 3.51905 |
| DENND2D | DENN/MADD domain containing 2D | 3.4683 |
| KIF20A | kinesin family member 20A | 3.32225 |
| C5 | complement component 5 | 3.1494 |
| HYOU1 | hypoxia up-regulated 1 | 3.14515 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 | 3.1338 |
| EGF | epidermal growth factor | 2.9547 |
| CCP110 | centriolar coiled coil protein 110kDa | 2.8459 |
| HEBP1 | heme binding protein 1 | 2.8271 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.7797 |
| ATP11B | ATPase, class VI, type 11B | 2.77585 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.62315 |
| RAB11FIP2 | RAB11 family interacting protein 2 (class I) | 2.5549 |
| CSK | c-src tyrosine kinase | 2.5485 |
| SIRT3 | sirtuin 3 | 2.46753 |
| INSIG1 | insulin induced gene 1 | 2.43167 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.34623 |
| MTREX | Mtr4 exosome RNA helicase | 2.2835 |
| B4GAT1 | beta-1,4-glucuronyltransferase 1 | 2.26615 |
| EVL | Enah/Vasp-like | 2.1684 |
| MYL7 | myosin, light chain 7, regulatory | 2.16055 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.10377 |
| ARL5A | ADP-ribosylation factor-like 5A | 2.03745 |
| SORBS3 | sorbin and SH3 domain containing 3 | 2.02638 |
| RNF44 | ring finger protein 44 | 2.0261 |
| FGB | fibrinogen beta chain | 2.0248 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.00113 |
| Symbol | Name | Standardized Value |
|---|---|---|
| INPP1 | inositol polyphosphate-1-phosphatase | -5.32955 |
| PCNA | proliferating cell nuclear antigen | -5.1435 |
| CD320 | CD320 molecule | -5.14245 |
| ZNF586 | zinc finger protein 586 | -4.8297 |
| GTPBP8 | GTP-binding protein 8 (putative) | -4.67145 |
| SLC35F2 | solute carrier family 35, member F2 | -4.585 |
| PRPF4 | pre-mRNA processing factor 4 | -4.51437 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -4.44555 |
| FASTKD5 | FAST kinase domains 5 | -4.164 |
| TLR4 | toll-like receptor 4 | -4.10845 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -4.03615 |
| SNX11 | sorting nexin 11 | -3.68157 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.5536 |
| NVL | nuclear VCP-like | -3.40775 |
| LOC124907782 | dual specificity protein phosphatase 22 | -3.3281 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -2.80803 |
| PSMB10 | proteasome (prosome, macropain) subunit, beta type, 10 | -2.7925 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | -2.73453 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.71327 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 | -2.39435 |
| ANOS1 | anosmin 1 | -2.3767 |
| TBX2 | T-box 2 | -2.37093 |
| FBXO28 | F-box protein 28 | -2.3682 |
| MTMR12 | myotubularin related protein 12 | -2.3677 |
| ACKR3 | atypical chemokine receptor 3 | -2.3491 |
| BIRC2 | baculoviral IAP repeat containing 2 | -2.28645 |
| TOR4A | torsin family 4, member A | -2.2616 |
| ZNF124 | zinc finger protein 124 | -2.23115 |
| XPA | xeroderma pigmentosum, complementation group A | -2.21125 |
| RGS2 | regulator of G-protein signaling 2 | -2.2083 |
| PRPF3 | pre-mRNA processing factor 3 | -2.20675 |
| NR2C2 | nuclear receptor subfamily 2, group C, member 2 | -2.20315 |
| GPATCH1 | G patch domain containing 1 | -2.13375 |
| TSTD2 | thiosulfate sulfurtransferase (rhodanese)-like domain containing 2 | -2.0705 |
| PARP2 | poly (ADP-ribose) polymerase 2 | -2.06437 |
| ZNF222 | zinc finger protein 222 | -2.01635 |
| ZFP69B | ZFP69 zinc finger protein B | -2.0038 |
