CRCGN014_HEPG2_3H:D12 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description dimethyl terephthalate 40.4 um perturbation at 3 h in HEPG2 (Carcinogenome)
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Genes

67 genes differentially expressed following the CRCGN014_HEPG2_3H:D12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 4.89967
CARMIL1 capping protein regulator and myosin 1 linker 1 4.82816
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 4.67474
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 4.4879
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 4.37446
MSRA methionine sulfoxide reductase A 4.26374
CIAO3 cytosolic iron-sulfur assembly component 3 4.19598
STIMATE STIM activating enhancer 4.1834
CBR3 carbonyl reductase 3 4.09398
LCN2 lipocalin 2 4.08624
KIF14 kinesin family member 14 3.99718
MAP7 microtubule-associated protein 7 3.87771
IKZF1 IKAROS family zinc finger 1 (Ikaros) 3.37309
MAP3K4 mitogen-activated protein kinase kinase kinase 4 3.27947
CYCS cytochrome c, somatic 3.26609
C2CD2 C2 calcium-dependent domain containing 2 3.26077
TIAM1 T-cell lymphoma invasion and metastasis 1 3.22271
ARID4B AT rich interactive domain 4B (RBP1-like) 3.20658
HOXA10 homeobox A10 3.0313
MYLK myosin light chain kinase 2.91626
STOM stomatin 2.88059
CEP57 centrosomal protein 57kDa 2.86681
GPER1 G protein-coupled estrogen receptor 1 2.5063
TEX10 testis expressed 10 2.48099
EPHA3 EPH receptor A3 2.45233
PSPN persephin 2.4438
CHEK2 checkpoint kinase 2 2.39663
PBLD phenazine biosynthesis-like protein domain containing 2.36564
A4GALT alpha 1,4-galactosyltransferase 2.35834
LHX6 LIM homeobox 6 2.20808
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.19767
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1 2.1593
GIPC2 GIPC PDZ domain containing family, member 2 2.14288
CHN1 chimerin 1 2.11511
ADRA2B adrenoceptor alpha 2B 2.10217
SLC17A1 solute carrier family 17 (organic anion transporter), member 1 2.0922
SDK2 sidekick cell adhesion molecule 2 2.07741
MORN1 MORN repeat containing 1 2.06365
TUBA8 tubulin, alpha 8 2.0429
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 2.04273
TRAM2 translocation associated membrane protein 2 2.03144
BAMBI BMP and activin membrane-bound inhibitor 2.02179
SLC13A1 solute carrier family 13 (sodium/sulfate symporter), member 1 2.0004

decreased expression

Symbol Name Standardized Value
CCNB2 cyclin B2 -5.14523
COG2 component of oligomeric golgi complex 2 -4.68648
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -4.64325
ZNF586 zinc finger protein 586 -4.50804
ZDHHC6 zinc finger, DHHC-type containing 6 -4.50118
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -4.39799
CDC20 cell division cycle 20 -4.366
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -4.14702
SLC35F2 solute carrier family 35, member F2 -3.78134
TRIB3 tribbles pseudokinase 3 -3.44932
HMG20B high mobility group 20B -2.97874
TXNDC9 thioredoxin domain containing 9 -2.95069
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -2.94937
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -2.92797
RFC2 replication factor C (activator 1) 2, 40kDa -2.87218
SPAG4 sperm associated antigen 4 -2.77198
CCDC86 coiled-coil domain containing 86 -2.76414
MAPK13 mitogen-activated protein kinase 13 -2.44658
AZGP1 alpha-2-glycoprotein 1, zinc-binding -2.35341
CTNND1 catenin (cadherin-associated protein), delta 1 -2.26803
OXA1L oxidase (cytochrome c) assembly 1-like -2.25759
HMOX1 heme oxygenase 1 -2.01899
TOMM70 translocase of outer mitochondrial membrane 70 -2.00871
DVL3 dishevelled segment polarity protein 3 -2.00082