CRCGN014_HEPG2_3H:D14 Gene Set
Genes
57 genes differentially expressed following the CRCGN014_HEPG2_3H:D14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
6.37626
|
|
JADE2
|
jade family PHD finger 2
|
5.28986
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
4.75749
|
|
RPL39L
|
ribosomal protein L39-like
|
4.44125
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
3.98092
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.93308
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.66885
|
|
SLC27A3
|
solute carrier family 27 (fatty acid transporter), member 3
|
3.66113
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.6595
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
3.61269
|
|
MOK
|
MOK protein kinase
|
3.54519
|
|
PLSCR1
|
phospholipid scramblase 1
|
3.51175
|
|
LSR
|
lipolysis stimulated lipoprotein receptor
|
3.05365
|
|
C5
|
complement component 5
|
2.99771
|
|
CCP110
|
centriolar coiled coil protein 110kDa
|
2.91482
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.76094
|
|
CCNF
|
cyclin F
|
2.7062
|
|
KIF14
|
kinesin family member 14
|
2.59819
|
|
EVL
|
Enah/Vasp-like
|
2.41846
|
|
CHN1
|
chimerin 1
|
2.41153
|
|
PCDHB11
|
protocadherin beta 11
|
2.40126
|
|
H2BC12
|
H2B clustered histone 12
|
2.38159
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.35885
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.34605
|
|
COPS7A
|
COP9 signalosome subunit 7A
|
2.32534
|
|
SAA2
|
serum amyloid A2
|
2.30304
|
|
GATA2
|
GATA binding protein 2
|
2.23623
|
|
PSMB8
|
proteasome (prosome, macropain) subunit, beta type, 8
|
2.19779
|
|
LBR
|
lamin B receptor
|
2.15459
|
|
ZC3H7A
|
zinc finger CCCH-type containing 7A
|
2.12181
|
|
EIF5A2
|
eukaryotic translation initiation factor 5A2
|
2.03997
|
|
NXPE3
|
neurexophilin and PC-esterase domain family, member 3
|
2.00378
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-9.54061
|
|
LDHD
|
lactate dehydrogenase D
|
-8.68081
|
|
VAT1
|
vesicle amine transport 1
|
-5.0428
|
|
YME1L1
|
YME1-like 1 ATPase
|
-4.26839
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.01217
|
|
TRIB3
|
tribbles pseudokinase 3
|
-3.91089
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.81286
|
|
DNTTIP2
|
deoxynucleotidyltransferase, terminal, interacting protein 2
|
-3.28934
|
|
CTSD
|
cathepsin D
|
-3.13386
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-3.02839
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.98765
|
|
PARP2
|
poly (ADP-ribose) polymerase 2
|
-2.70856
|
|
IFRD2
|
interferon-related developmental regulator 2
|
-2.67444
|
|
NVL
|
nuclear VCP-like
|
-2.61724
|
|
GNAS
|
GNAS complex locus
|
-2.61006
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-2.60419
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.49181
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.3976
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.30724
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.30005
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-2.19604
|
|
RALA
|
v-ral simian leukemia viral oncogene homolog A (ras related)
|
-2.10816
|
|
DNAJC15
|
DnaJ (Hsp40) homolog, subfamily C, member 15
|
-2.08763
|
|
ZNF185
|
zinc finger protein 185 (LIM domain)
|
-2.08547
|
|
OSGIN1
|
oxidative stress induced growth inhibitor 1
|
-2.04003
|
