CRCGN014_HEPG2_3H:D15 Gene Set
Genes
37 genes differentially expressed following the CRCGN014_HEPG2_3H:D15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CYCS
|
cytochrome c, somatic
|
6.24776
|
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
5.18414
|
|
GPATCH8
|
G patch domain containing 8
|
5.04201
|
|
TERT
|
telomerase reverse transcriptase
|
4.96728
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.86728
|
|
UBQLN2
|
ubiquilin 2
|
4.49508
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.63784
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
3.48423
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.24897
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
2.78603
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.60132
|
|
CEP57
|
centrosomal protein 57kDa
|
2.57035
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.5589
|
|
PRR15L
|
proline rich 15-like
|
2.47412
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.45273
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
2.26341
|
|
IL2RG
|
interleukin 2 receptor, gamma
|
2.01706
|
|
TMEM126B
|
transmembrane protein 126B
|
2.00736
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-9.71106
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-5.12763
|
|
CDC20
|
cell division cycle 20
|
-5.06633
|
|
LDHD
|
lactate dehydrogenase D
|
-4.77459
|
|
HSPB1
|
heat shock 27kDa protein 1
|
-4.62439
|
|
HAT1
|
histone acetyltransferase 1
|
-4.06001
|
|
BNIP3L
|
BCL2/adenovirus E1B 19kDa interacting protein 3-like
|
-3.99478
|
|
TRIB3
|
tribbles pseudokinase 3
|
-3.71519
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.71058
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.67008
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.48336
|
|
TLR4
|
toll-like receptor 4
|
-3.25592
|
|
HMG20B
|
high mobility group 20B
|
-3.16746
|
|
GNAS
|
GNAS complex locus
|
-2.85661
|
|
EGF
|
epidermal growth factor
|
-2.70291
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.62358
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-2.50063
|
|
TBX2
|
T-box 2
|
-2.35354
|
|
CCDC15
|
coiled-coil domain containing 15
|
-2.10949
|
