CRCGN014_HEPG2_3H:D16 Gene Set
Genes
34 genes differentially expressed following the CRCGN014_HEPG2_3H:D16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
7.16048
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
5.46663
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
5.44536
|
|
CBR3
|
carbonyl reductase 3
|
3.92718
|
|
HOXA10
|
homeobox A10
|
3.71614
|
|
BAMBI
|
BMP and activin membrane-bound inhibitor
|
3.37553
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
3.23981
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
3.07873
|
|
MSRA
|
methionine sulfoxide reductase A
|
2.86547
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.59258
|
|
ZNF589
|
zinc finger protein 589
|
2.4368
|
|
CSK
|
c-src tyrosine kinase
|
2.34576
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
2.33062
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
2.25872
|
|
PLSCR1
|
phospholipid scramblase 1
|
2.2433
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.19818
|
|
ABHD4
|
abhydrolase domain containing 4
|
2.16836
|
|
ABHD6
|
abhydrolase domain containing 6
|
2.07211
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-5.59225
|
|
GOLT1B
|
golgi transport 1B
|
-4.29265
|
|
CDC20
|
cell division cycle 20
|
-4.25168
|
|
YME1L1
|
YME1-like 1 ATPase
|
-3.11889
|
|
VAT1
|
vesicle amine transport 1
|
-3.0244
|
|
NFKBIA
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
|
-3.01799
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.7816
|
|
CCNB2
|
cyclin B2
|
-2.57577
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-2.50305
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.43429
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.37442
|
|
LAP3
|
leucine aminopeptidase 3
|
-2.32576
|
|
NVL
|
nuclear VCP-like
|
-2.12771
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.05346
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.04654
|
|
VEGFD
|
vascular endothelial growth factor D
|
-2.01287
|