CRCGN014_HEPG2_3H:D16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description trichlorofluoromethane 40.0 um perturbation at 3 h in HEPG2 (Carcinogenome)
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Genes

34 genes differentially expressed following the CRCGN014_HEPG2_3H:D16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 7.16048
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 5.46663
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 5.44536
CBR3 carbonyl reductase 3 3.92718
HOXA10 homeobox A10 3.71614
BAMBI BMP and activin membrane-bound inhibitor 3.37553
ADGRE5 adhesion G protein-coupled receptor E5 3.23981
ANO1 anoctamin 1, calcium activated chloride channel 3.07873
MSRA methionine sulfoxide reductase A 2.86547
CXCL2 chemokine (C-X-C motif) ligand 2 2.59258
ZNF589 zinc finger protein 589 2.4368
CSK c-src tyrosine kinase 2.34576
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 2.33062
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 2.25872
PLSCR1 phospholipid scramblase 1 2.2433
GSTZ1 glutathione S-transferase zeta 1 2.19818
ABHD4 abhydrolase domain containing 4 2.16836
ABHD6 abhydrolase domain containing 6 2.07211

decreased expression

Symbol Name Standardized Value
LDHD lactate dehydrogenase D -5.59225
GOLT1B golgi transport 1B -4.29265
CDC20 cell division cycle 20 -4.25168
YME1L1 YME1-like 1 ATPase -3.11889
VAT1 vesicle amine transport 1 -3.0244
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -3.01799
NGRN neugrin, neurite outgrowth associated -2.7816
CCNB2 cyclin B2 -2.57577
UBE3C ubiquitin protein ligase E3C -2.50305
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -2.43429
PCNA proliferating cell nuclear antigen -2.37442
LAP3 leucine aminopeptidase 3 -2.32576
NVL nuclear VCP-like -2.12771
FGFR4 fibroblast growth factor receptor 4 -2.05346
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -2.04654
VEGFD vascular endothelial growth factor D -2.01287