CRCGN014_HEPG2_3H:D17 Gene Set
Genes
54 genes differentially expressed following the CRCGN014_HEPG2_3H:D17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAP7
|
microtubule-associated protein 7
|
5.68391
|
|
UBQLN2
|
ubiquilin 2
|
5.32224
|
|
MAMLD1
|
mastermind-like domain containing 1
|
5.30028
|
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
4.49991
|
|
PLCB3
|
phospholipase C, beta 3 (phosphatidylinositol-specific)
|
4.03797
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
3.94736
|
|
PRKCH
|
protein kinase C, eta
|
3.90822
|
|
STAP2
|
signal transducing adaptor family member 2
|
3.85138
|
|
STK10
|
serine/threonine kinase 10
|
3.80335
|
|
EPHB2
|
EPH receptor B2
|
3.67848
|
|
CRK
|
v-crk avian sarcoma virus CT10 oncogene homolog
|
3.63606
|
|
KIF14
|
kinesin family member 14
|
3.49206
|
|
PLSCR1
|
phospholipid scramblase 1
|
3.17857
|
|
CGRRF1
|
cell growth regulator with ring finger domain 1
|
3.14287
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
2.94236
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
2.84904
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.65846
|
|
PTK2
|
protein tyrosine kinase 2
|
2.53377
|
|
SNX7
|
sorting nexin 7
|
2.51255
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.49817
|
|
HYOU1
|
hypoxia up-regulated 1
|
2.20448
|
|
TBP
|
TATA box binding protein
|
2.20162
|
|
CEP57
|
centrosomal protein 57kDa
|
2.15091
|
|
NABP2
|
nucleic acid binding protein 2
|
2.14605
|
|
ENTPD7
|
ectonucleoside triphosphate diphosphohydrolase 7
|
2.09642
|
|
RBKS
|
ribokinase
|
2.00422
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-5.67092
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-5.33664
|
|
LDHD
|
lactate dehydrogenase D
|
-4.60153
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.18373
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-4.0199
|
|
CCNB2
|
cyclin B2
|
-3.88822
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.12346
|
|
GNAS
|
GNAS complex locus
|
-3.00122
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.93906
|
|
NVL
|
nuclear VCP-like
|
-2.81953
|
|
ZNF586
|
zinc finger protein 586
|
-2.80268
|
|
ADIPOR2
|
adiponectin receptor 2
|
-2.67077
|
|
CDC25B
|
cell division cycle 25B
|
-2.55034
|
|
CCNB1
|
cyclin B1
|
-2.45607
|
|
TRAPPC6A
|
trafficking protein particle complex 6A
|
-2.16038
|
|
NDUFS1
|
NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
|
-2.16022
|
|
MPHOSPH6
|
M-phase phosphoprotein 6
|
-2.15553
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.13114
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.11616
|
|
PARP2
|
poly (ADP-ribose) polymerase 2
|
-2.08685
|
|
METTL17
|
methyltransferase like 17
|
-2.08465
|
|
EGF
|
epidermal growth factor
|
-2.08408
|
|
MAPK6
|
mitogen-activated protein kinase 6
|
-2.07579
|
|
HSD17B2
|
hydroxysteroid (17-beta) dehydrogenase 2
|
-2.03677
|
|
PTGFR
|
prostaglandin F receptor (FP)
|
-2.03377
|
|
ARL4D
|
ADP-ribosylation factor-like 4D
|
-2.03185
|
|
ATP6V0C
|
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
|
-2.01322
|
|
STARD7
|
StAR-related lipid transfer (START) domain containing 7
|
-2.01131
|
