CRCGN014_HEPG2_3H:D19 Gene Set
Genes
53 genes differentially expressed following the CRCGN014_HEPG2_3H:D19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
UBQLN2
|
ubiquilin 2
|
6.41587
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
4.70777
|
|
LSR
|
lipolysis stimulated lipoprotein receptor
|
4.06423
|
|
MCOLN1
|
mucolipin 1
|
3.63203
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
3.4538
|
|
PRR15L
|
proline rich 15-like
|
3.05647
|
|
LCN2
|
lipocalin 2
|
2.9894
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.96003
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.77163
|
|
C5
|
complement component 5
|
2.72567
|
|
HOXA10
|
homeobox A10
|
2.68523
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.61756
|
|
ALAS1
|
5'-aminolevulinate synthase 1
|
2.61463
|
|
KIF20A
|
kinesin family member 20A
|
2.60607
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.5796
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.51927
|
|
VGLL4
|
vestigial-like family member 4
|
2.48465
|
|
EZH2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
2.4531
|
|
CYCS
|
cytochrome c, somatic
|
2.39213
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.28973
|
|
TBP
|
TATA box binding protein
|
2.21143
|
|
MAP7
|
microtubule-associated protein 7
|
2.19433
|
|
ARB2A
|
ARB2 cotranscriptional regulator A
|
2.15193
|
|
BMP4
|
bone morphogenetic protein 4
|
2.11727
|
|
DENND1C
|
DENN/MADD domain containing 1C
|
2.092
|
|
TERT
|
telomerase reverse transcriptase
|
2.08667
|
|
IQGAP1
|
IQ motif containing GTPase activating protein 1
|
2.06637
|
|
ZAP70
|
zeta-chain (TCR) associated protein kinase 70kDa
|
2.02667
|
|
CETP
|
cholesteryl ester transfer protein, plasma
|
2.00573
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-6.9007
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-5.83223
|
|
GNAS
|
GNAS complex locus
|
-4.97405
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-4.4952
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-4.27103
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.808
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.61843
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.53357
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-3.4593
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-3.44003
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-3.39267
|
|
DNM1L
|
dynamin 1-like
|
-3.1758
|
|
ZNF586
|
zinc finger protein 586
|
-3.10567
|
|
CDC20
|
cell division cycle 20
|
-2.9896
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.91757
|
|
FASTKD5
|
FAST kinase domains 5
|
-2.91557
|
|
PARP2
|
poly (ADP-ribose) polymerase 2
|
-2.91186
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-2.89086
|
|
HAT1
|
histone acetyltransferase 1
|
-2.85773
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.35443
|
|
WASHC4
|
WASH complex subunit 4
|
-2.19552
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.19055
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-2.08657
|
|
CCNB1
|
cyclin B1
|
-2.07893
|
