| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | iq 21.02 um perturbation at 3 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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54 genes differentially expressed following the CRCGN014_HEPG2_3H:D21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 6.84248 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 6.59335 |
| MAP7 | microtubule-associated protein 7 | 5.43108 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 3.9949 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 3.38824 |
| KLHL21 | kelch-like family member 21 | 3.38149 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 3.24665 |
| CHMP6 | charged multivesicular body protein 6 | 3.21528 |
| CEP57 | centrosomal protein 57kDa | 3.21395 |
| ADRB2 | adrenoceptor beta 2, surface | 3.01308 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.74654 |
| EPHA3 | EPH receptor A3 | 2.74423 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.70593 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 2.67916 |
| KRT24 | keratin 24, type I | 2.53413 |
| HOXA10 | homeobox A10 | 2.51448 |
| CLDN15 | claudin 15 | 2.48514 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.45235 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 2.44407 |
| PRR15L | proline rich 15-like | 2.37994 |
| STIMATE | STIM activating enhancer | 2.32486 |
| ATP11B | ATPase, class VI, type 11B | 2.31569 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.31268 |
| DCPH1 | damage control phosphatase 1 | 2.28954 |
| CYCS | cytochrome c, somatic | 2.2315 |
| VNN1 | vanin 1 | 2.22313 |
| BAK1 | BCL2-antagonist/killer 1 | 2.19232 |
| BAMBI | BMP and activin membrane-bound inhibitor | 2.18173 |
| MRPL30 | mitochondrial ribosomal protein L30 | 2.06298 |
| CLCN7 | chloride channel, voltage-sensitive 7 | 2.05545 |
| TM4SF20 | transmembrane 4 L six family member 20 | 2.02283 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -9.64377 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -6.88359 |
| GNAS | GNAS complex locus | -5.23879 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -4.60545 |
| CDC20 | cell division cycle 20 | -3.81537 |
| ZNF586 | zinc finger protein 586 | -3.70548 |
| KDM3A | lysine (K)-specific demethylase 3A | -3.70426 |
| MRPS2 | mitochondrial ribosomal protein S2 | -3.57865 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -3.35365 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -3.20885 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.18336 |
| LDHD | lactate dehydrogenase D | -3.11067 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -3.0803 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -2.98774 |
| VAT1 | vesicle amine transport 1 | -2.75081 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.5065 |
| PCNA | proliferating cell nuclear antigen | -2.35278 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.34266 |
| TNNT1 | troponin T type 1 (skeletal, slow) | -2.20655 |
| RAI14 | retinoic acid induced 14 | -2.18489 |
| PEG10 | paternally expressed 10 | -2.17578 |
| ADAR | adenosine deaminase, RNA-specific | -2.08832 |
| DOCK3 | dedicator of cytokinesis 3 | -2.01714 |
