| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | thioacetamide 40.4 um perturbation at 3 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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65 genes differentially expressed following the CRCGN014_HEPG2_3H:D22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 9.13636 |
| STK10 | serine/threonine kinase 10 | 8.17071 |
| NOTCH1 | notch 1 | 4.96241 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.48401 |
| SFTPB | surfactant protein B | 4.46954 |
| COG4 | component of oligomeric golgi complex 4 | 4.30656 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | 4.18348 |
| STIMATE | STIM activating enhancer | 3.94484 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 3.66196 |
| CYCS | cytochrome c, somatic | 3.35064 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.29972 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 3.203 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | 2.76176 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 2.66628 |
| CDC45 | cell division cycle 45 | 2.62144 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 2.60964 |
| GRB10 | growth factor receptor-bound protein 10 | 2.60136 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.59221 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 2.39839 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 2.35085 |
| FKBP14 | FK506 binding protein 14, 22 kDa | 2.27443 |
| SMIM40 | small integral membrane protein 40 | 2.2456 |
| BAHD1 | bromo adjacent homology domain containing 1 | 2.18361 |
| SIRT3 | sirtuin 3 | 2.17858 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.16393 |
| ATP7B | ATPase, Cu++ transporting, beta polypeptide | 2.14605 |
| ASXL2 | additional sex combs like transcriptional regulator 2 | 2.08571 |
| SYCP2 | synaptonemal complex protein 2 | 2.06248 |
| USP12 | ubiquitin specific peptidase 12 | 2.04251 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -10.0 |
| MAPK13 | mitogen-activated protein kinase 13 | -7.35731 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -6.60948 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.93117 |
| CDC20 | cell division cycle 20 | -4.56118 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -4.50977 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.45046 |
| CD320 | CD320 molecule | -4.42298 |
| ADI1 | acireductone dioxygenase 1 | -4.39374 |
| TLR4 | toll-like receptor 4 | -4.34787 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -4.18058 |
| NCK1 | NCK adaptor protein 1 | -3.44686 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -3.36412 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.26287 |
| AURKB | aurora kinase B | -3.0033 |
| ZNF586 | zinc finger protein 586 | -2.98624 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.7573 |
| BIRC2 | baculoviral IAP repeat containing 2 | -2.65082 |
| WASHC4 | WASH complex subunit 4 | -2.50059 |
| ELP5 | elongator acetyltransferase complex subunit 5 | -2.38636 |
| GPBP1L1 | GC-rich promoter binding protein 1-like 1 | -2.33436 |
| TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | -2.21368 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 | -2.16975 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -2.15125 |
| CDHR1 | cadherin-related family member 1 | -2.14833 |
| TCEAL4 | transcription elongation factor A (SII)-like 4 | -2.12965 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.12466 |
| ECHDC1 | ethylmalonyl-CoA decarboxylase 1 | -2.12348 |
| RAB25 | RAB25, member RAS oncogene family | -2.0849 |
| SLURP1 | secreted LY6/PLAUR domain containing 1 | -2.07061 |
| PLAAT3 | phospholipase A and acyltransferase 3 | -2.05061 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -2.04571 |
| IGFBP6 | insulin-like growth factor binding protein 6 | -2.03986 |
| RGS2 | regulator of G-protein signaling 2 | -2.01494 |
| DUSP11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | -2.00766 |
| PGM1 | phosphoglucomutase 1 | -2.00047 |
