CRCGN014_HEPG2_3H:D23 Gene Set
Genes
33 genes differentially expressed following the CRCGN014_HEPG2_3H:D23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
3.89333
|
|
MYLK
|
myosin light chain kinase
|
3.48532
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.40628
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.34146
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.2432
|
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
3.22041
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.19157
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
2.96641
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.95191
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
2.84483
|
|
HOXA10
|
homeobox A10
|
2.52073
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.47017
|
|
SQOR
|
sulfide quinone oxidoreductase
|
2.34402
|
|
ABHD6
|
abhydrolase domain containing 6
|
2.28466
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.22673
|
|
ZBTB18
|
zinc finger and BTB domain containing 18
|
2.19277
|
|
DECR2
|
2,4-dienoyl CoA reductase 2, peroxisomal
|
2.03313
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-5.95308
|
|
VAT1
|
vesicle amine transport 1
|
-3.39843
|
|
LDHD
|
lactate dehydrogenase D
|
-3.34971
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-3.16705
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-2.97015
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.90106
|
|
TRIB3
|
tribbles pseudokinase 3
|
-2.75013
|
|
CCNB2
|
cyclin B2
|
-2.66186
|
|
YME1L1
|
YME1-like 1 ATPase
|
-2.61821
|
|
GTPBP8
|
GTP-binding protein 8 (putative)
|
-2.55471
|
|
TLR4
|
toll-like receptor 4
|
-2.49523
|
|
CSK
|
c-src tyrosine kinase
|
-2.39389
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.38106
|
|
ZBTB24
|
zinc finger and BTB domain containing 24
|
-2.16872
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-2.09868
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.05183
|
