CRCGN014_HEPG2_3H:E01 Gene Set
Genes
57 genes differentially expressed following the CRCGN014_HEPG2_3H:E01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CCDC85B
|
coiled-coil domain containing 85B
|
6.08811
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
6.03145
|
|
E2F2
|
E2F transcription factor 2
|
5.15126
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
4.60616
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.49958
|
|
MAMLD1
|
mastermind-like domain containing 1
|
4.38831
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
4.22298
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
4.09314
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.07975
|
|
EPHB2
|
EPH receptor B2
|
4.07059
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.02414
|
|
PRR15L
|
proline rich 15-like
|
3.98424
|
|
HDGFL3
|
HDGF like 3
|
3.7804
|
|
CSK
|
c-src tyrosine kinase
|
3.7161
|
|
ZNF589
|
zinc finger protein 589
|
3.53911
|
|
CHN1
|
chimerin 1
|
3.49819
|
|
JADE2
|
jade family PHD finger 2
|
3.48738
|
|
NUP133
|
nucleoporin 133kDa
|
3.32186
|
|
ASCC3
|
activating signal cointegrator 1 complex subunit 3
|
3.03166
|
|
KLHL9
|
kelch-like family member 9
|
2.77431
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.72575
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.72229
|
|
NOTCH1
|
notch 1
|
2.66838
|
|
MAP7
|
microtubule-associated protein 7
|
2.63427
|
|
ZBTB18
|
zinc finger and BTB domain containing 18
|
2.60781
|
|
HOXA10
|
homeobox A10
|
2.51682
|
|
CYCS
|
cytochrome c, somatic
|
2.51022
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.47597
|
|
HMGCR
|
3-hydroxy-3-methylglutaryl-CoA reductase
|
2.43252
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.38075
|
|
UBR7
|
ubiquitin protein ligase E3 component n-recognin 7 (putative)
|
2.28341
|
|
PTN
|
pleiotrophin
|
2.16405
|
|
PIH1D1
|
PIH1 domain containing 1
|
2.15382
|
|
RRAGA
|
Ras-related GTP binding A
|
2.14895
|
|
HEBP1
|
heme binding protein 1
|
2.13764
|
|
ILK
|
integrin-linked kinase
|
2.08466
|
|
CEND1
|
cell cycle exit and neuronal differentiation 1
|
2.03655
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-7.05058
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-6.59804
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-5.67136
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-4.60611
|
|
CDC20
|
cell division cycle 20
|
-4.33653
|
|
DCK
|
deoxycytidine kinase
|
-4.01917
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-3.52881
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-3.33076
|
|
ANKRD10
|
ankyrin repeat domain 10
|
-3.29792
|
|
SNX11
|
sorting nexin 11
|
-3.17885
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.06891
|
|
SPAG4
|
sperm associated antigen 4
|
-2.86556
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.71408
|
|
NCK2
|
NCK adaptor protein 2
|
-2.47341
|
|
TBC1D31
|
TBC1 domain family, member 31
|
-2.28528
|
|
GGNBP2
|
gametogenetin binding protein 2
|
-2.27996
|
|
NRDC
|
nardilysin convertase
|
-2.13572
|
|
CENPX
|
centromere protein X
|
-2.074
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-2.03599
|
|
MAP2K5
|
mitogen-activated protein kinase kinase 5
|
-2.01243
|
