CRCGN014_HEPG2_3H:E03 Gene Set
Genes
41 genes differentially expressed following the CRCGN014_HEPG2_3H:E03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CYCS
|
cytochrome c, somatic
|
6.0126
|
|
MAP7
|
microtubule-associated protein 7
|
4.71445
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
4.26388
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
4.0495
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
3.73155
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.59265
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
3.56351
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
3.52602
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.22012
|
|
PRKCH
|
protein kinase C, eta
|
2.97713
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.80691
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.77318
|
|
HPRT1
|
hypoxanthine phosphoribosyltransferase 1
|
2.71096
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.46106
|
|
ABHD6
|
abhydrolase domain containing 6
|
2.31162
|
|
SQOR
|
sulfide quinone oxidoreductase
|
2.29262
|
|
CBR3
|
carbonyl reductase 3
|
2.24474
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.16631
|
|
HYAL2
|
hyaluronoglucosaminidase 2
|
2.15244
|
|
JADE2
|
jade family PHD finger 2
|
2.14644
|
|
UFM1
|
ubiquitin-fold modifier 1
|
2.05116
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-8.23162
|
|
TLR4
|
toll-like receptor 4
|
-6.60835
|
|
RPS4Y1
|
ribosomal protein S4, Y-linked 1
|
-6.37387
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-5.76525
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-5.31178
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-4.94183
|
|
CDC20
|
cell division cycle 20
|
-4.41861
|
|
LDHD
|
lactate dehydrogenase D
|
-4.03015
|
|
CCNB2
|
cyclin B2
|
-3.95921
|
|
LAP3
|
leucine aminopeptidase 3
|
-3.7459
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-3.70454
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.14212
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-2.97288
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-2.92396
|
|
PAEP
|
progestagen-associated endometrial protein
|
-2.32435
|
|
ADCY7
|
adenylate cyclase 7
|
-2.14952
|
|
DRC3
|
dynein regulatory complex subunit 3
|
-2.14106
|
|
EXD2
|
exonuclease 3'-5' domain containing 2
|
-2.04946
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.01147
|
|
SLC25A13
|
solute carrier family 25 (aspartate/glutamate carrier), member 13
|
-2.00727
|
