| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | dichloroacetic-acid 41.0 um perturbation at 3 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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112 genes differentially expressed following the CRCGN014_HEPG2_3H:E04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 5.97551 |
| DIPK1A | divergent protein kinase domain 1A | 5.57807 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 5.31821 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 5.20333 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.88489 |
| GSTZ1 | glutathione S-transferase zeta 1 | 4.65307 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 4.02202 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 3.91768 |
| CORO1A | coronin, actin binding protein, 1A | 3.66593 |
| CCDC85B | coiled-coil domain containing 85B | 3.629 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 3.62127 |
| PTK2 | protein tyrosine kinase 2 | 3.48236 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 3.33443 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 3.27929 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 3.18309 |
| KIFBP | kinesin family binding protein | 3.08029 |
| SHB | Src homology 2 domain containing adaptor protein B | 3.01146 |
| CYB561 | cytochrome b561 | 2.98346 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 2.7973 |
| RAB21 | RAB21, member RAS oncogene family | 2.77801 |
| PLCL1 | phospholipase C-like 1 | 2.76078 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 2.70983 |
| MEST | mesoderm specific transcript | 2.70014 |
| NVL | nuclear VCP-like | 2.65503 |
| ZNF12 | zinc finger protein 12 | 2.65169 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | 2.60007 |
| ILK | integrin-linked kinase | 2.54748 |
| GHR | growth hormone receptor | 2.5302 |
| ROGDI | rogdi homolog (Drosophila) | 2.42773 |
| CAPN1 | calpain 1, (mu/I) large subunit | 2.42112 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.38832 |
| ARMCX1 | armadillo repeat containing, X-linked 1 | 2.31421 |
| MFAP5 | microfibrillar associated protein 5 | 2.26656 |
| NOP53 | NOP53 ribosome biogenesis factor | 2.24454 |
| RPS5 | ribosomal protein S5 | 2.24036 |
| TMEM204 | transmembrane protein 204 | 2.20969 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 2.18774 |
| PTK2B | protein tyrosine kinase 2 beta | 2.17803 |
| COPS4 | COP9 signalosome subunit 4 | 2.16941 |
| ARL4C | ADP-ribosylation factor-like 4C | 2.1684 |
| AHCY | adenosylhomocysteinase | 2.1616 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 2.14864 |
| ARMCX5-GPRASP2 | ARMCX5-GPRASP2 readthrough | 2.13778 |
| INTS5 | integrator complex subunit 5 | 2.1181 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 2.11723 |
| TRAPPC6A | trafficking protein particle complex 6A | 2.11564 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 2.11469 |
| ZNF362 | zinc finger protein 362 | 2.10524 |
| ICE1 | interactor of little elongation complex ELL subunit 1 | 2.10242 |
| PPP1R16B | protein phosphatase 1, regulatory subunit 16B | 2.09866 |
| LPAR6 | lysophosphatidic acid receptor 6 | 2.08664 |
| IPO13 | importin 13 | 2.07878 |
| CLN3 | ceroid-lipofuscinosis, neuronal 3 | 2.07153 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 | 2.06865 |
| TRIM8 | tripartite motif containing 8 | 2.06732 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 | 2.03457 |
| PGAP6 | post-GPI attachment to proteins 6 | 2.03401 |
| FMNL3 | formin-like 3 | 2.03066 |
| BSN | bassoon presynaptic cytomatrix protein | 2.02789 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 | 2.0063 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -5.92073 |
| GOLT1B | golgi transport 1B | -5.4943 |
| PCNA | proliferating cell nuclear antigen | -5.30458 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -4.87997 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -4.66462 |
| ANKRD10 | ankyrin repeat domain 10 | -4.3065 |
| SLC35F2 | solute carrier family 35, member F2 | -4.24043 |
| TOMM34 | translocase of outer mitochondrial membrane 34 | -4.21798 |
| FGFR4 | fibroblast growth factor receptor 4 | -3.79136 |
| TBC1D31 | TBC1 domain family, member 31 | -3.73762 |
| TLR4 | toll-like receptor 4 | -3.72777 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.6825 |
| CCNB2 | cyclin B2 | -3.6303 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -3.6141 |
| CSK | c-src tyrosine kinase | -3.41031 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -3.28932 |
| G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 | -3.17412 |
| GLOD4 | glyoxalase domain containing 4 | -3.12999 |
| LAGE3 | L antigen family, member 3 | -2.80032 |
| CMAS | cytidine monophosphate N-acetylneuraminic acid synthetase | -2.5749 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -2.51767 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -2.51378 |
| EMID1 | EMI domain containing 1 | -2.35872 |
| TCTN1 | tectonic family member 1 | -2.30415 |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) | -2.28378 |
| ACYP1 | acylphosphatase 1, erythrocyte (common) type | -2.25698 |
| TLCD3A | TLC domain containing 3A | -2.25192 |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 | -2.20677 |
| RUVBL1 | RuvB-like AAA ATPase 1 | -2.17932 |
| LGMN | legumain | -2.17929 |
| CDC123 | cell division cycle 123 | -2.17089 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -2.1691 |
| KRT10 | keratin 10, type I | -2.16335 |
| SPAG4 | sperm associated antigen 4 | -2.15463 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -2.15193 |
| ALDH18A1 | aldehyde dehydrogenase 18 family, member A1 | -2.13878 |
| FAM216A | family with sequence similarity 216, member A | -2.13781 |
| RECQL | RecQ helicase-like | -2.13086 |
| VRK2 | vaccinia related kinase 2 | -2.12203 |
| NEK4 | NIMA-related kinase 4 | -2.12002 |
| STAMBP | STAM binding protein | -2.11628 |
| CYBA | cytochrome b-245, alpha polypeptide | -2.09063 |
| NFIL3 | nuclear factor, interleukin 3 regulated | -2.08175 |
| STN1 | STN1 subunit of CST complex | -2.07202 |
| VAT1 | vesicle amine transport 1 | -2.07094 |
| HEATR3 | HEAT repeat containing 3 | -2.05456 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | -2.03071 |
| WDR4 | WD repeat domain 4 | -2.02614 |
| COL9A3 | collagen, type IX, alpha 3 | -2.02364 |
| CD320 | CD320 molecule | -2.01262 |
| MRPS16 | mitochondrial ribosomal protein S16 | -2.00454 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -2.00311 |
