| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | diphenyl-p-phenylenediamine 39.8 um perturbation at 3 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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74 genes differentially expressed following the CRCGN014_HEPG2_3H:E09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CYCS | cytochrome c, somatic | 7.50883 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 6.20754 |
| STAP2 | signal transducing adaptor family member 2 | 5.38795 |
| CBR3 | carbonyl reductase 3 | 5.23643 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 5.12411 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 4.83736 |
| UBQLN2 | ubiquilin 2 | 4.76945 |
| STIMATE | STIM activating enhancer | 4.71615 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 4.19219 |
| E2F2 | E2F transcription factor 2 | 3.77277 |
| PMM2 | phosphomannomutase 2 | 3.48238 |
| FZD7 | frizzled class receptor 7 | 3.20754 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 3.08534 |
| KIFBP | kinesin family binding protein | 2.98734 |
| ABHD6 | abhydrolase domain containing 6 | 2.9644 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 2.81223 |
| TBP | TATA box binding protein | 2.78612 |
| CHN1 | chimerin 1 | 2.7501 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 2.70256 |
| UBE2A | ubiquitin-conjugating enzyme E2A | 2.6054 |
| CCNF | cyclin F | 2.56689 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 2.55449 |
| PLSCR1 | phospholipid scramblase 1 | 2.42797 |
| KDSR | 3-ketodihydrosphingosine reductase | 2.40348 |
| CTR9 | CTR9, Paf1/RNA polymerase II complex component | 2.32043 |
| ATP5F1D | ATP synthase F1 subunit delta | 2.31876 |
| TBXA2R | thromboxane A2 receptor | 2.2911 |
| GRB10 | growth factor receptor-bound protein 10 | 2.27837 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 2.27735 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 2.21823 |
| CHAF1A | chromatin assembly factor 1, subunit A (p150) | 2.17563 |
| CDT1 | chromatin licensing and DNA replication factor 1 | 2.16043 |
| MX1 | MX dynamin-like GTPase 1 | 2.14721 |
| SLC75A1 | solute carrier family 75 member 1 | 2.14116 |
| NPDC1 | neural proliferation, differentiation and control, 1 | 2.13907 |
| TMOD1 | tropomodulin 1 | 2.07555 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZNF586 | zinc finger protein 586 | -7.39439 |
| CCNB2 | cyclin B2 | -6.59653 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -6.31112 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -5.47173 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.86992 |
| VAT1 | vesicle amine transport 1 | -4.43568 |
| NISCH | nischarin | -4.31611 |
| TLR4 | toll-like receptor 4 | -3.84083 |
| SNX11 | sorting nexin 11 | -3.62018 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -3.5557 |
| CCNB1 | cyclin B1 | -3.5352 |
| TBC1D31 | TBC1 domain family, member 31 | -3.39984 |
| RFC2 | replication factor C (activator 1) 2, 40kDa | -3.39617 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.37732 |
| SLC35F2 | solute carrier family 35, member F2 | -3.25691 |
| DUSP11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | -3.18435 |
| AURKB | aurora kinase B | -3.14941 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -3.08977 |
| SPAG4 | sperm associated antigen 4 | -3.07768 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -2.96115 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.61539 |
| WASHC4 | WASH complex subunit 4 | -2.53829 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.5342 |
| CDK1 | cyclin-dependent kinase 1 | -2.49589 |
| NDFIP1 | Nedd4 family interacting protein 1 | -2.44658 |
| SPI1 | Spi-1 proto-oncogene | -2.32444 |
| MPC2 | mitochondrial pyruvate carrier 2 | -2.29525 |
| GRWD1 | glutamate-rich WD repeat containing 1 | -2.28708 |
| TRAPPC6A | trafficking protein particle complex 6A | -2.21314 |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase | -2.19817 |
| RHEB | Ras homolog enriched in brain | -2.16791 |
| TTC27 | tetratricopeptide repeat domain 27 | -2.16153 |
| TRMT13 | tRNA methyltransferase 13 homolog (S. cerevisiae) | -2.14002 |
| SCCPDH | saccharopine dehydrogenase (putative) | -2.12233 |
| TCTN1 | tectonic family member 1 | -2.11069 |
| EIF2D | eukaryotic translation initiation factor 2D | -2.10969 |
| ATP6V1A | ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A | -2.08533 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.04913 |
