| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | hydrazine sulfate 40.0 um perturbation at 3 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
76 genes differentially expressed following the CRCGN014_HEPG2_3H:E10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 10.0 |
| CRTAP | cartilage associated protein | 5.2355 |
| PNKP | polynucleotide kinase 3'-phosphatase | 5.1584 |
| LCN2 | lipocalin 2 | 4.99435 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 4.88045 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 4.83625 |
| CGRRF1 | cell growth regulator with ring finger domain 1 | 4.74095 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 4.5167 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.4245 |
| MEF2C | myocyte enhancer factor 2C | 4.08452 |
| PRKCH | protein kinase C, eta | 3.9828 |
| CYCS | cytochrome c, somatic | 3.8964 |
| CHN1 | chimerin 1 | 3.8693 |
| SIRT3 | sirtuin 3 | 3.17365 |
| ILK | integrin-linked kinase | 3.07245 |
| EGF | epidermal growth factor | 3.0411 |
| VGLL4 | vestigial-like family member 4 | 2.87077 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 2.7727 |
| SFTPB | surfactant protein B | 2.7536 |
| LRRC17 | leucine rich repeat containing 17 | 2.6865 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.67558 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 | 2.62525 |
| GPATCH8 | G patch domain containing 8 | 2.55212 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 2.53745 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 2.42373 |
| GATA2 | GATA binding protein 2 | 2.30977 |
| COCH | cochlin | 2.26615 |
| NUP133 | nucleoporin 133kDa | 2.2526 |
| STUM | stum, mechanosensory transduction mediator homolog | 2.227 |
| ZFHX4 | zinc finger homeobox 4 | 2.21245 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 | 2.1535 |
| EVL | Enah/Vasp-like | 2.1141 |
| CTR9 | CTR9, Paf1/RNA polymerase II complex component | 2.0944 |
| NDUFS4 | NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) | 2.0938 |
| IRF7 | interferon regulatory factor 7 | 2.08345 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 2.07765 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 | 2.0638 |
| SNX7 | sorting nexin 7 | 2.06185 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 2.05595 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 2.04155 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 2.01215 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SCAND1 | SCAN domain containing 1 | -5.2395 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -5.11325 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.98585 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -4.97845 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.85445 |
| VAT1 | vesicle amine transport 1 | -4.7603 |
| CCNB2 | cyclin B2 | -4.63915 |
| PLK1 | polo-like kinase 1 | -4.4659 |
| CHMP4B | charged multivesicular body protein 4B | -4.3087 |
| TLR4 | toll-like receptor 4 | -3.85875 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -3.8418 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.31715 |
| TRAPPC6A | trafficking protein particle complex 6A | -3.23735 |
| SPAG4 | sperm associated antigen 4 | -3.1663 |
| PALB2 | partner and localizer of BRCA2 | -2.93825 |
| ASAH1 | N-acylsphingosine amidohydrolase (acid ceramidase) 1 | -2.51868 |
| TOR3A | torsin family 3, member A | -2.4675 |
| RBM15 | RNA binding motif protein 15 | -2.39852 |
| LIN28A | lin-28 homolog A (C. elegans) | -2.3612 |
| CAB39 | calcium binding protein 39 | -2.33635 |
| KDM7A | lysine (K)-specific demethylase 7A | -2.31355 |
| IGSF6 | immunoglobulin superfamily, member 6 | -2.28095 |
| DPPA4 | developmental pluripotency associated 4 | -2.2358 |
| DCK | deoxycytidine kinase | -2.2321 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 | -2.1397 |
| FOXJ3 | forkhead box J3 | -2.13958 |
| H1-3 | H1.3 linker histone, cluster member | -2.12155 |
| PMM2 | phosphomannomutase 2 | -2.08515 |
| UTP6 | UTP6, small subunit (SSU) processome component, homolog (yeast) | -2.08355 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -2.05297 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -2.03425 |
| KLF1 | Kruppel-like factor 1 (erythroid) | -2.02065 |
| DGKQ | diacylglycerol kinase, theta 110kDa | -2.01275 |
| L1TD1 | LINE-1 type transposase domain containing 1 | -2.0078 |
| OFD1 | oral-facial-digital syndrome 1 | -2.0052 |
