CRCGN014_HEPG2_3H:E16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description prednisolone 39.6 um perturbation at 3 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

45 genes differentially expressed following the CRCGN014_HEPG2_3H:E16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
PPARG peroxisome proliferator-activated receptor gamma 8.62049
GSTZ1 glutathione S-transferase zeta 1 7.70467
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 5.53599
CCDC92 coiled-coil domain containing 92 5.30431
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 5.2576
GPATCH8 G patch domain containing 8 4.74423
EPHB2 EPH receptor B2 4.26151
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 4.09903
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3 3.79107
MAP7 microtubule-associated protein 7 3.70749
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.64651
UBE2L6 ubiquitin-conjugating enzyme E2L 6 3.64192
PFKL phosphofructokinase, liver 3.50159
CARMIL1 capping protein regulator and myosin 1 linker 1 3.47053
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 2.70646
PCDHB11 protocadherin beta 11 2.68309
PMM2 phosphomannomutase 2 2.61401
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.54343
BAMBI BMP and activin membrane-bound inhibitor 2.4909
KCNK1 potassium channel, two pore domain subfamily K, member 1 2.43559
PRL prolactin 2.36936
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 2.33226
PWP2 PWP2 periodic tryptophan protein homolog (yeast) 2.23343
TIMP4 TIMP metallopeptidase inhibitor 4 2.17445
LONRF3 LON peptidase N-terminal domain and ring finger 3 2.13142
SLC25A46 solute carrier family 25, member 46 2.11472
GPHN gephyrin 2.09702
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.05231
GATD3 glutamine amidotransferase class 1 domain containing 3 2.04206
KRT4 keratin 4, type II 2.02669
MLH3 mutL homolog 3 2.01871

decreased expression

Symbol Name Standardized Value
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -6.06585
CDC20 cell division cycle 20 -5.04037
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -4.71008
ZNF586 zinc finger protein 586 -4.34751
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -3.92399
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -3.65423
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma -3.44935
TXNDC9 thioredoxin domain containing 9 -3.06293
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2 -3.04299
GNAS GNAS complex locus -2.85981
OXA1L oxidase (cytochrome c) assembly 1-like -2.72659
DCK deoxycytidine kinase -2.72202
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.66381
MAPK13 mitogen-activated protein kinase 13 -2.52736