CRCGN014_HEPG2_3H:E18 Gene Set
Genes
35 genes differentially expressed following the CRCGN014_HEPG2_3H:E18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAP7
|
microtubule-associated protein 7
|
5.5985
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.77726
|
|
CBR3
|
carbonyl reductase 3
|
4.43963
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.2009
|
|
MSRA
|
methionine sulfoxide reductase A
|
3.43839
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
3.41354
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
3.03167
|
|
MEF2C
|
myocyte enhancer factor 2C
|
2.64315
|
|
UBQLN2
|
ubiquilin 2
|
2.58141
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.46248
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.3523
|
|
FKBP14
|
FK506 binding protein 14, 22 kDa
|
2.30701
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
2.30576
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.18656
|
|
EXOSC4
|
exosome component 4
|
2.16741
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
2.10408
|
|
CDK19
|
cyclin-dependent kinase 19
|
2.02742
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-5.44658
|
|
TLCD3A
|
TLC domain containing 3A
|
-4.58195
|
|
ZNF586
|
zinc finger protein 586
|
-4.10963
|
|
NFKBIA
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
|
-3.35993
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-3.14061
|
|
LDHD
|
lactate dehydrogenase D
|
-2.74232
|
|
SLC25A13
|
solute carrier family 25 (aspartate/glutamate carrier), member 13
|
-2.64549
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.57887
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.56802
|
|
CCNB2
|
cyclin B2
|
-2.55808
|
|
CSK
|
c-src tyrosine kinase
|
-2.48065
|
|
THAP11
|
THAP domain containing 11
|
-2.47737
|
|
DNAJC15
|
DnaJ (Hsp40) homolog, subfamily C, member 15
|
-2.35179
|
|
WASHC4
|
WASH complex subunit 4
|
-2.27676
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.22798
|
|
TLR4
|
toll-like receptor 4
|
-2.12093
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.05978
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-2.03478
|
