CRCGN014_HEPG2_3H:E20 Gene Set
Genes
39 genes differentially expressed following the CRCGN014_HEPG2_3H:E20 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
6.80891
|
|
ABHD6
|
abhydrolase domain containing 6
|
5.45176
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.95133
|
|
MAMLD1
|
mastermind-like domain containing 1
|
3.78256
|
|
STK10
|
serine/threonine kinase 10
|
3.57616
|
|
LAGE3
|
L antigen family, member 3
|
3.3301
|
|
HOXA10
|
homeobox A10
|
3.25354
|
|
DDX10
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
|
3.18885
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.10552
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
2.95754
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.82449
|
|
GATA2
|
GATA binding protein 2
|
2.80883
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
2.78228
|
|
LSR
|
lipolysis stimulated lipoprotein receptor
|
2.68042
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
2.56631
|
|
NOTCH1
|
notch 1
|
2.52198
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
2.41496
|
|
STIMATE
|
STIM activating enhancer
|
2.3899
|
|
CSK
|
c-src tyrosine kinase
|
2.23285
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.22796
|
|
HPRT1
|
hypoxanthine phosphoribosyltransferase 1
|
2.17222
|
|
CEP57
|
centrosomal protein 57kDa
|
2.11042
|
|
MCUR1
|
mitochondrial calcium uniporter regulator 1
|
2.0856
|
|
VGLL4
|
vestigial-like family member 4
|
2.06811
|
|
KIF14
|
kinesin family member 14
|
2.01914
|
|
MAP7
|
microtubule-associated protein 7
|
2.01122
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
GNAS
|
GNAS complex locus
|
-4.41661
|
|
CPSF4
|
cleavage and polyadenylation specific factor 4, 30kDa
|
-4.18754
|
|
ZNF586
|
zinc finger protein 586
|
-3.97709
|
|
CCDC86
|
coiled-coil domain containing 86
|
-3.94187
|
|
DNM1L
|
dynamin 1-like
|
-3.87904
|
|
CCNB2
|
cyclin B2
|
-3.4185
|
|
TLR4
|
toll-like receptor 4
|
-3.19508
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.0371
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.93956
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.53843
|
|
HMOX1
|
heme oxygenase 1
|
-2.29391
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.29139
|
|
CCNB1
|
cyclin B1
|
-2.22162
|
