CRCGN014_HEPG2_3H:E21 Gene Set
Genes
30 genes differentially expressed following the CRCGN014_HEPG2_3H:E21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NOTCH1
|
notch 1
|
4.87216
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.28139
|
|
TIMM22
|
translocase of inner mitochondrial membrane 22 homolog (yeast)
|
3.98897
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
3.78354
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.69359
|
|
MAP7
|
microtubule-associated protein 7
|
3.68376
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.66285
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.57009
|
|
BAX
|
BCL2-associated X protein
|
3.26211
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.19822
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.12167
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.64405
|
|
DHDDS
|
dehydrodolichyl diphosphate synthase
|
2.63682
|
|
ATP11B
|
ATPase, class VI, type 11B
|
2.50032
|
|
JADE2
|
jade family PHD finger 2
|
2.49007
|
|
BMP4
|
bone morphogenetic protein 4
|
2.37187
|
|
SFTPB
|
surfactant protein B
|
2.37067
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
2.23254
|
|
ZBTB18
|
zinc finger and BTB domain containing 18
|
2.04673
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.48411
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.28405
|
|
LDHD
|
lactate dehydrogenase D
|
-4.23526
|
|
VAT1
|
vesicle amine transport 1
|
-4.20139
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.1305
|
|
HMG20B
|
high mobility group 20B
|
-3.49359
|
|
TLR4
|
toll-like receptor 4
|
-3.21345
|
|
PGM1
|
phosphoglucomutase 1
|
-2.59043
|
|
EGF
|
epidermal growth factor
|
-2.3013
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.10989
|
|
TRIB3
|
tribbles pseudokinase 3
|
-2.01367
|
