CRCGN014_HEPG2_3H:E22 Gene Set
Genes
53 genes differentially expressed following the CRCGN014_HEPG2_3H:E22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAP7
|
microtubule-associated protein 7
|
7.09436
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.94113
|
|
MAMLD1
|
mastermind-like domain containing 1
|
4.73153
|
|
NOTCH1
|
notch 1
|
4.55092
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
4.37948
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
4.07965
|
|
TIPARP
|
TCDD-inducible poly(ADP-ribose) polymerase
|
4.01714
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
3.99539
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
3.75646
|
|
UBQLN2
|
ubiquilin 2
|
3.6713
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.46576
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.37897
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.33865
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
3.02525
|
|
CYCS
|
cytochrome c, somatic
|
2.81731
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.7495
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
2.65351
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.60951
|
|
TNIP1
|
TNFAIP3 interacting protein 1
|
2.40542
|
|
CHN1
|
chimerin 1
|
2.38068
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.30166
|
|
IGSF6
|
immunoglobulin superfamily, member 6
|
2.17606
|
|
ZEB2
|
zinc finger E-box binding homeobox 2
|
2.11098
|
|
MTM1
|
myotubularin 1
|
2.09894
|
|
ENTREP2
|
endosomal transmembrane epsin interactor 2
|
2.05632
|
|
KLHDC8A
|
kelch domain containing 8A
|
2.05393
|
|
MOCS2
|
molybdenum cofactor synthesis 2
|
2.02722
|
|
TXNL4B
|
thioredoxin-like 4B
|
2.0211
|
|
LIPC
|
lipase, hepatic
|
2.00246
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-9.11535
|
|
TLCD3A
|
TLC domain containing 3A
|
-4.84737
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-4.33812
|
|
HAT1
|
histone acetyltransferase 1
|
-4.00337
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-3.86212
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-3.71224
|
|
DNM1L
|
dynamin 1-like
|
-3.66455
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-3.37876
|
|
WASHC4
|
WASH complex subunit 4
|
-3.00358
|
|
CD320
|
CD320 molecule
|
-2.77048
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
-2.73298
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.7105
|
|
EMILIN1
|
elastin microfibril interfacer 1
|
-2.65804
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.61186
|
|
GDF15
|
growth differentiation factor 15
|
-2.16317
|
|
HIF1A
|
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
|
-2.15904
|
|
TBC1D17
|
TBC1 domain family, member 17
|
-2.12435
|
|
PROS1
|
protein S (alpha)
|
-2.08317
|
|
ZNF134
|
zinc finger protein 134
|
-2.07834
|
|
GFRA3
|
GDNF family receptor alpha 3
|
-2.03935
|
|
COL5A1
|
collagen, type V, alpha 1
|
-2.03121
|
|
BCL9
|
B-cell CLL/lymphoma 9
|
-2.01703
|
|
PTGS2
|
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
|
-2.00991
|
|
PTK7
|
protein tyrosine kinase 7 (inactive)
|
-2.00443
|
