| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | hydrazobenzene 40.4 um perturbation at 3 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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56 genes differentially expressed following the CRCGN014_HEPG2_3H:E23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.84439 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.81176 |
| GPATCH8 | G patch domain containing 8 | 4.7442 |
| MSRA | methionine sulfoxide reductase A | 4.57273 |
| MYLK | myosin light chain kinase | 4.44491 |
| CSK | c-src tyrosine kinase | 3.43917 |
| DENND2D | DENN/MADD domain containing 2D | 3.31609 |
| AXIN1 | axin 1 | 3.28193 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 3.13416 |
| DIPK1A | divergent protein kinase domain 1A | 3.11573 |
| GSTZ1 | glutathione S-transferase zeta 1 | 3.08056 |
| PIH1D1 | PIH1 domain containing 1 | 3.05443 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) | 2.89769 |
| SOCS2 | suppressor of cytokine signaling 2 | 2.87589 |
| RXYLT1 | ribitol xylosyltransferase 1 | 2.73631 |
| DYNC1I1 | dynein, cytoplasmic 1, intermediate chain 1 | 2.67963 |
| MAP7 | microtubule-associated protein 7 | 2.67803 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta | 2.65653 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.54567 |
| TNIP1 | TNFAIP3 interacting protein 1 | 2.47936 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 2.38209 |
| CCDC85B | coiled-coil domain containing 85B | 2.34298 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 2.23187 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 2.17408 |
| PSMB3 | proteasome (prosome, macropain) subunit, beta type, 3 | 2.10191 |
| MRPS31 | mitochondrial ribosomal protein S31 | 2.09393 |
| NIT1 | nitrilase 1 | 2.06594 |
| STON1 | stonin 1 | 2.03177 |
| ANXA2 | annexin A2 | 2.01688 |
| DUOX2 | dual oxidase 2 | 2.00477 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -9.34219 |
| MAPK13 | mitogen-activated protein kinase 13 | -7.39448 |
| PCNA | proliferating cell nuclear antigen | -5.5554 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.86269 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -4.47456 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -4.3626 |
| ZNF586 | zinc finger protein 586 | -4.02825 |
| EIF5 | eukaryotic translation initiation factor 5 | -3.73705 |
| CCNB2 | cyclin B2 | -3.69461 |
| CD58 | CD58 molecule | -3.65735 |
| TCTN1 | tectonic family member 1 | -2.95674 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.83864 |
| NVL | nuclear VCP-like | -2.76421 |
| UBE3C | ubiquitin protein ligase E3C | -2.57303 |
| EGF | epidermal growth factor | -2.46054 |
| PROS1 | protein S (alpha) | -2.4115 |
| PRPF4 | pre-mRNA processing factor 4 | -2.37365 |
| PEG10 | paternally expressed 10 | -2.34104 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -2.269 |
| SNX11 | sorting nexin 11 | -2.2346 |
| SMC4 | structural maintenance of chromosomes 4 | -2.16731 |
| APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C | -2.15971 |
| TMEM168 | transmembrane protein 168 | -2.08037 |
| RFWD3 | ring finger and WD repeat domain 3 | -2.06779 |
| BIRC2 | baculoviral IAP repeat containing 2 | -2.06667 |
| DNASE2B | deoxyribonuclease II beta | -2.00722 |
