CRCGN014_HEPG2_3H:E24 Gene Set
Genes
56 genes differentially expressed following the CRCGN014_HEPG2_3H:E24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CYCS
|
cytochrome c, somatic
|
5.59408
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
5.20414
|
|
STIMATE
|
STIM activating enhancer
|
5.11115
|
|
CSK
|
c-src tyrosine kinase
|
4.80469
|
|
SFTPB
|
surfactant protein B
|
3.8995
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
3.38831
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
3.37759
|
|
ZNF589
|
zinc finger protein 589
|
3.28125
|
|
RRAGA
|
Ras-related GTP binding A
|
3.22811
|
|
LCN2
|
lipocalin 2
|
3.20715
|
|
PLSCR3
|
phospholipid scramblase 3
|
3.09915
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.05603
|
|
MAMLD1
|
mastermind-like domain containing 1
|
3.00079
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.65999
|
|
SATB1
|
SATB homeobox 1
|
2.61849
|
|
MEST
|
mesoderm specific transcript
|
2.58559
|
|
SIRT3
|
sirtuin 3
|
2.54454
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.33807
|
|
CTSL
|
cathepsin L
|
2.33687
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
2.3346
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
2.29162
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.24408
|
|
NPC2
|
Niemann-Pick disease, type C2
|
2.22622
|
|
EVL
|
Enah/Vasp-like
|
2.18621
|
|
HPX
|
hemopexin
|
2.14987
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.13524
|
|
SNRPA
|
small nuclear ribonucleoprotein polypeptide A
|
2.10918
|
|
ARRB2
|
arrestin, beta 2
|
2.08384
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.0639
|
|
WBP11
|
WW domain binding protein 11
|
2.04346
|
|
ADA2
|
adenosine deaminase 2
|
2.02754
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-6.62772
|
|
LDHD
|
lactate dehydrogenase D
|
-4.97191
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-4.9624
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.52102
|
|
TLCD3A
|
TLC domain containing 3A
|
-4.19174
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-3.5766
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.14393
|
|
THAP11
|
THAP domain containing 11
|
-3.13474
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.92323
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.91504
|
|
SNX11
|
sorting nexin 11
|
-2.82435
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.7159
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-2.69593
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-2.67703
|
|
HMG20B
|
high mobility group 20B
|
-2.50045
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.49951
|
|
GNAS
|
GNAS complex locus
|
-2.46149
|
|
TRIB3
|
tribbles pseudokinase 3
|
-2.28901
|
|
AZGP1
|
alpha-2-glycoprotein 1, zinc-binding
|
-2.24006
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-2.21274
|
|
CHEK1
|
checkpoint kinase 1
|
-2.19874
|
|
HSPA8
|
heat shock 70kDa protein 8
|
-2.17866
|
|
BIRC2
|
baculoviral IAP repeat containing 2
|
-2.12602
|
|
ZNF93
|
zinc finger protein 93
|
-2.09909
|
|
ZFP30
|
ZFP30 zinc finger protein
|
-2.03695
|
